Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.46 |
| ▸ | PNMT | P11086 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7414917 | 0.78 | TAAR1 (0.50) | KCNN4PNMTTAAR1HTR2AHTR2C | |
| SCHEMBL1431670 | 0.74 | KCNN4 (0.56) | KCNN4PNMTTAAR1HTR2AHTR2C | |
| SCHEMBL3669301 | 0.74 | KCNN4 (0.56) | KCNN4PNMTTAAR1HTR2AHTR2C | |
| SCHEMBL31521320 | 0.74 | KCNN4 (0.56) | KCNN4PNMTTAAR1HTR2AHTR2C | |
| SCHEMBL12439704 | 0.74 | HTR2A (0.42) | KCNN4PNMTTAAR1HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL2320513 | 0.73 | HTR2A (0.41) | KCNN4PNMTTAAR1HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL23886201 | 0.73 | KCNN4 (0.54) | KCNN4PNMTTAAR1HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL29857899 | 0.73 | KCNN4 (0.54) | KCNN4PNMTTAAR1HTR2AHTR2C | |
| SCHEMBL6912370 | 0.73 | KCNN4 (0.54) | KCNN4PNMTTAAR1HTR2AHTR2C | |
| SCHEMBL19265162 | 0.72 | KCNN4 (0.48) | KCNN4PNMTTAAR1HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070066624-A1 | Chemokine receptor binding compounds | ANORMED, INC. (CA) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066624-A1 | Chemokine receptor binding compounds | CCR5, CCR4, CCR1 | KCNN4 4831/4885PNMT 3831/4885TAAR1 915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.