Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.77 |
| ▸ | PPARG | P37231 | 7/20 | 0.77 |
| ▸ | PPARD | Q03181 | 7/20 | 0.77 |
| ▸ | PPARA | Q07869 | 7/20 | 0.77 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.77 |
| ▸ | TSHR | P16473 | 4/20 | 0.77 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.77 |
| ▸ | FABP4 | P15090 | 3/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.77 |
| ▸ | TLR2 | O60603 | 2/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.77 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.77 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.77 |
| ▸ | MEN1 | O00255 | 1/20 | 0.77 |
| ▸ | ESR1 | P03372 | 1/20 | 0.77 |
| ▸ | PDE4A | P27815 | 1/20 | 0.77 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Octanoic Acid SCHEMBL3414554 | 1.00 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Decanoic Acid SCHEMBL5875269 | 1.00 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanoic Acid SCHEMBL3412884 | 1.00 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Heptanoate SCHEMBL3410001 | 1.00 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Undecanoate SCHEMBL21145218 | 1.00 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dodecanoate SCHEMBL8469515 | 1.00 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Nonanoate SCHEMBL5874090 | 1.00 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanoic Acid SCHEMBL28159534 | 0.98 | GPR84 (0.74) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL28986985 | 0.98 | GPR84 (0.74) | GPR84PPARGPPARDPPARAHDAC11 | |
| Hexanoate SCHEMBL3411666 | 0.98 | AKR1B1 (0.76) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160199027-A1 | ULTRASOUND PROBE COUPLERS AND RELATED METHODS | SCULLY, CASEY K. | 2016-07-14 | — | — | US | claimed |
| WO-2006114140-A1 | PRISTANIC ACID-CONTAINING COSMETIC PREPARATIONS | BEIERSDORF AG (DE) | 2006-11-02 | — | — | WO | claimed |
| US-5863524-A | INCLUDING A POLYAMINE CLARIFIER WITH AN ALKALI METAL BICARBONATE OR CARBONATE, A POLYHYDRIC ALCOHOL, A FATTY ACID SALT AND WATER; STABILITY; FEEL | CHURCH & DWIGHT CO., INC. (US) | 1999-01-26 | — | — | US | claimed |
| EP-3538225-B1 | ALUMINUM-FREE ANTIPERSPIRANT/DEODORANT COMPOSITIONS | COLGATE PALMOLIVE CO (US) | 2026-04-01 | — | — | EP | disclosed |
| US-20240325266-A1 | Personal Care Compositions | COLGATE-PALMOLIVE COMPANY (US) | 2024-10-03 | — | — | US | disclosed |
| US-20230340317-A1 | METHOD AND APPLICATIONS OF NONSTOICHIOMETRIC IONIC EMULSIONS | SAUDI ARABIAN OIL COMPANY (SA) | 2023-10-26 | — | — | US | disclosed |
| EP-2948505-B1 | THERMOPLASTIC COMPOSITIONS CONTAINING NANOSCALE-SIZED PARTICLE ADDITIVES FOR LASER DIRECT STRUCTURING AND METHODS FOR THE MANUFACTURE AND USE THEREOF | SHPP GLOBAL TECH BV (NL) | 2022-11-16 | — | — | EP | disclosed |
| US-11147755-B2 | Aluminum-free antiperspirant / deodorant compositions | COLGATE-PALMOLIVE COMPANY (US) | 2021-10-19 | — | — | US | disclosed |
| CN-107158050-B | Hydrangea paniculata total coumarin glycoside, preparation method, composition and application thereof | 中国医学科学院药物研究所 | 2021-08-13 | — | — | CN | disclosed |
| CN-104447900-B | Preparation activity, application and quality control of new compound | 石任兵 | 2021-08-06 | — | — | CN | disclosed |
| CN-103989966-B | Medicine composition for preventing and treating migraine disease and preparation method and application thereof | 石任兵 | 2021-05-25 | — | — | CN | disclosed |
| US-5241003-A | Post-treated polyisobutenyl succinimide; crankcase, transmission oils | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1993-08-31 | — | — | US | disclosed |
| EP-0531585-A1 | Oil additive concentrates and lubricants of enhanced performance capabilities | ETHYL PETROLEUM ADDITIVES LIMITED (GB) | 1993-03-17 | — | — | EP | disclosed |
| EP-0531000-A1 | Oil additive concentrates and lubricants of enhanced performance capabilities | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1993-03-10 | — | — | EP | disclosed |
| US-5137980-A | Reacting polyisobutene with aacidic reactant; super atmospheric pressure; low tar rating | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1992-08-11 | — | — | US | disclosed |
| EP-0459656-A1 | Lubricant compositions | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1991-12-04 | — | — | EP | disclosed |
| US-5066743-A | Bonding nonpolar surfaces such as polyethylene and polypropylene | LOCTITE CORPORATION (US) | 1991-11-19 | — | — | US | disclosed |
| EP-0430624-A1 | Gear oils and additives therefor | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1991-06-05 | — | — | EP | disclosed |
| EP-0428393-A1 | Gear oils and additives therefor | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1991-05-22 | — | — | EP | disclosed |
| US-4979993-A | Trialkylammonium alkyl carboxylate primer for cyanoacrylate bonding of polymeric substrates | LOCTITE CORPORATION (US) | 1990-12-25 | — | — | US | disclosed |