Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.36 |
| ▸ | DPP4 | P27487 | 4/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.36 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ARG1 | P05089 | 1/20 | 0.33 |
| ▸ | ARG2 | P78540 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL18259132 | 1.00 | GSR (0.48) | GSRDPP7DPP4DPP8DPP9 | |
| Lysine SCHEMBL1675274 | 0.96 | GSR (0.51) | GSRDPP7DPP4DPP8DPP9 | |
| Lysine SCHEMBL5575951 | 0.96 | GSR (0.51) | GSRDPP7DPP4DPP8DPP9 | |
| Lysine SCHEMBL29069496 | 0.96 | GSR (0.51) | GSRDPP7DPP4DPP8DPP9 | |
| Lysine SCHEMBL16038745 | 0.95 | GSR (0.53) | GSRDPP7DPP4DPP8DPP9 | |
| Lysine SCHEMBL22157986 | 0.95 | GSR (0.53) | GSRDPP7DPP4DPP8DPP9 | |
| Lysine SCHEMBL21796038 | 0.95 | GSR (0.53) | GSRDPP7DPP4DPP8DPP9 | |
| Lysine SCHEMBL1675387 | 0.95 | GSR (0.53) | GSRDPP7DPP4DPP8DPP9 | |
| Lysine SCHEMBL6276264 | 0.95 | GSR (0.53) | GSRDPP7DPP4DPP8DPP9 | |
| Lysine SCHEMBL3094553 | 0.95 | GSR (0.53) | GSRDPP7DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3302577-A1 | OPTIMISED MULTIVALENT TARGETING FLUORESCENT TRACER | Fluoptics (FR) | 2018-04-11 | — | — | EP | disclosed |
| WO-2016189007-A1 | OPTIMISED MULTIVALENT TARGETING FLUORESCENT TRACER | FLUOPTICS (FR) | 2016-12-01 | — | — | WO | disclosed |