Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 12/20 | 0.57 |
| ▸ | CCR4 | P51679 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5576066 | 1.00 | CCR5 (0.57) | CCR5CCR4KCNH2OPRM1OPRL1 | |
| SCHEMBL4656708 | 0.93 | CCR5 (0.60) | CCR5CCR4KCNH2 | |
| SCHEMBL4656713 | 0.93 | CCR5 (0.60) | CCR5CCR4KCNH2 | |
| SCHEMBL14614283 | 0.91 | CCR5 (0.58) | CCR5CCR4KCNH2 | |
| SCHEMBL4627241 | 0.88 | CCR5 (0.72) | CCR5CCR4KCNH2 | |
| SCHEMBL4627240 | 0.88 | CCR5 (0.72) | CCR5CCR4KCNH2 | |
| SCHEMBL5573802 | 0.85 | CCR5 (0.61) | CCR5CCR4KCNH2KMT2A | |
| SCHEMBL5573794 | 0.85 | CCR5 (0.61) | CCR5CCR4KCNH2KMT2A | |
| SCHEMBL5576306 | 0.84 | CCR5 (0.59) | CCR5CCR4KCNH2 | |
| SCHEMBL5576320 | 0.84 | CCR5 (0.59) | CCR5CCR4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070066624-A1 | Chemokine receptor binding compounds | ANORMED, INC. (CA) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066624-A1 | Chemokine receptor binding compounds | CCR5, CCR4, CCR1 | CCR5 1/4885CCR4 2/4885KCNH2 4762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.