SCHEMBL5576151

SCHEMBL5576151

C=C(Br)Cc1ccccc1C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 4/20 0.52
ALDH1A1 P00352 5/20 0.48
ALOX15 P16050 1/20 0.48
TSHR P16473 1/20 0.47
TP53 P04637 1/20 0.42
HTT P42858 1/20 0.42
BCAT2 O15382 1/20 0.42
KDM4E B2RXH2 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
HMGB1 P09429 1/20 0.42
HPGD P15428 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
CA7 P43166 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CA9 Q16790 1/20 0.42
NAPRT Q6XQN6 1/20 0.42
CA14 Q9ULX7 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8662241 0.84 FOLH1 (0.55) FOLH1ALDH1A1ALOX15TSHRTP53
SCHEMBL28820710 0.83 KDM4E (0.44) ALDH1A1TSHRBCAT2KDM4EHPGD
SCHEMBL11443185 0.82 FOLH1 (0.57) FOLH1ALDH1A1ALOX15TSHRTP53
SCHEMBL6401722 0.81 FOLH1 (0.52) FOLH1ALDH1A1ALOX15TSHRTP53
SCHEMBL5575616 0.81 FOLH1 (0.52) FOLH1ALDH1A1ALOX15TSHRTP53
SCHEMBL3969116 0.81 FOLH1 (0.52) FOLH1ALDH1A1ALOX15TSHRTP53
SCHEMBL6530167 0.79 FOLH1 (0.59) FOLH1ALDH1A1ALOX15TSHRTP53
2-Carboxybenzeneacetic Acid SCHEMBL27477 0.79 AKR1B1 (0.61) FOLH1ALDH1A1ALOX15TSHRTP53
2-Carboxybenzeneacetic Acid SCHEMBL1891118 0.79 AKR1B1 (0.61) FOLH1ALDH1A1ALOX15TSHRTP53
SCHEMBL8710388 0.78 FOLH1 (0.49) FOLH1ALDH1A1ALOX15TSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7296576-B2 Polymers for enhanced solubility of nanomaterials, compositions and methods therefor ZYVEX PERFORMANCE MATERIALS, LLC (US) 2007-11-20 US disclosed
US-20060041104-A1 Polymers for enhanced solubility of nanomaterials, compositions and methods therefor ZYVEX CORPORATION (US) 2006-02-23 US disclosed