Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12013904 | 0.88 | FOLH1 (0.52) | FOLH1ALDH1A1ALOX15TSHRKDM4E | |
| 2-Carboxybenzeneacetic Acid SCHEMBL1891118 | 0.86 | AKR1B1 (0.61) | FOLH1ALDH1A1ALOX15TSHRKDM4E | |
| 2-Carboxybenzeneacetic Acid SCHEMBL27477 | 0.86 | AKR1B1 (0.61) | FOLH1ALDH1A1ALOX15TSHRKDM4E | |
| SCHEMBL9464875 | 0.85 | FOLH1 (0.49) | FOLH1ALDH1A1ALOX15TSHRKDM4E | |
| SCHEMBL28332847 | 0.85 | FOLH1 (0.49) | FOLH1ALDH1A1ALOX15TSHRKDM4E | |
| SCHEMBL29158552 | 0.85 | FOLH1 (0.53) | FOLH1ALDH1A1ALOX15TSHRKDM4E | |
| 2-Carboxybenzeneacetic Acid SCHEMBL3975685 | 0.84 | BCAT2 (0.59) | FOLH1ALDH1A1ALOX15TSHRKDM4E | |
| SCHEMBL11443185 | 0.84 | FOLH1 (0.57) | FOLH1ALDH1A1ALOX15TSHRKDM4E | |
| 2-Carboxybenzeneacetic Acid SCHEMBL4828304 | 0.84 | BCAT2 (0.59) | FOLH1ALDH1A1ALOX15TSHRKDM4E | |
| SCHEMBL6824473 | 0.83 | KDM4E (0.53) | FOLH1ALDH1A1ALOX15TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115298180-B | Compounds for treating or inhibiting recurrence of acute myeloid leukemia | 日本理化学研究所 | 2025-06-10 | — | — | CN | disclosed |
| US-20050043411-A1 | Process for preparing homophthalate derivatives | TJGEL, LLC | 2005-02-24 | — | — | US | disclosed |
| US-6797838-B2 | Process for preparing homophthalate derivatives | ILEX PRODUCTS, INC. | 2004-09-28 | — | — | US | disclosed |
| EP-1404662-A2 | PROCESS FOR PREPARING ISOCOUMARINS | Ilex Products, Inc. (US) | 2004-04-07 | — | — | EP | disclosed |
| US-20040024240-A1 | Process for preparing homophthalate derivatives | GENZYME CORPORATION | 2004-02-05 | — | — | US | disclosed |
| US-6664401-B2 | Reacting a isochroman-1,3-dione with a carbonyl compound whose carbonyl group is substituted with an acyl activating group, in the presence of a base and a solvent; use making anticancer agents for example | ILEX PRODUCTS, INC. | 2003-12-16 | — | — | US | disclosed |
| US-20030105340-A1 | Process for preparing isocoumarins | GENZYME CORPORATION | 2003-06-05 | — | — | US | disclosed |
| WO-2003004486-A2 | PROCESS FOR PREPARING ISOCOUMARINS | ILEX PRODUCTS, INC. (US) | 2003-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105340-A1 | Process for preparing isocoumarins | DHPS, IDH2, IDH1 | FOLH1 2953/4885ALDH1A1 1178/4885ALOX15 997/4885 |
| US-20050043411-A1 | Process for preparing homophthalate derivatives | HPD, HAAO, PAH | FOLH1 1472/4885ALDH1A1 669/4885ALOX15 2246/4885 |
| US-20040024240-A1 | Process for preparing homophthalate derivatives | HPD, HAAO, PAH | FOLH1 1472/4885ALDH1A1 669/4885ALOX15 2246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.