Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.48 |
| ▸ | DPP4 | P27487 | 5/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.46 |
| ▸ | FAP | Q12884 | 2/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1257864 | 0.88 | LMNA (0.53) | LMNADPP7DPP4DPP8DPP9 | |
| SCHEMBL30608510 | 0.84 | DPP4 (0.50) | LMNADPP7DPP4DPP8DPP9 | |
| SCHEMBL1296384 | 0.83 | LMNA (0.48) | LMNADPP7DPP4DPP8DPP9 | |
| SCHEMBL27824844 | 0.83 | LMNA (0.48) | LMNADPP7DPP4DPP8DPP9 | |
| SCHEMBL31256537 | 0.83 | GRB2 (0.49) | — | |
| SCHEMBL11435718 | 0.82 | NAMPT (0.48) | LMNANAMPTTRPV1PABPC1MEN1 | |
| SCHEMBL219560 | 0.82 | FKBP4 (0.41) | KMT2A | |
| SCHEMBL5835132 | 0.82 | FKBP4 (0.41) | KMT2A | |
| Hydrochloric Acid SCHEMBL6673589 | 0.81 | FKBP4 (0.41) | KMT2A | |
| Hydrochloric Acid SCHEMBL10448676 | 0.81 | FKBP4 (0.41) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070100561-A1 | Crystals of DPP-IV | HENNIG MICHAEL | 2007-05-03 | — | — | US | disclosed |
| US-20070015269-A1 | Crystals of DPP-IV | HOFFMANN-LA ROCHE INC. | 2007-01-18 | — | — | US | disclosed |
| EP-1422293-A1 | Crystal structure of dipeptidyl peptidase IV | F. HOFFMANN-LA ROCHE AG (CH) | 2004-05-26 | — | — | EP | disclosed |