Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | CXCR3 | P49682 | 6/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3312846 | 0.89 | HDAC6 (0.48) | PTPN1KCNA5KDM4EALDH1A1HDAC6 | |
| SCHEMBL3314317 | 0.87 | HDAC6 (0.46) | PTPN1KCNA5KDM4EALDH1A1HDAC6 | |
| SCHEMBL3313097 | 0.82 | HDAC6 (0.42) | PTPN1KCNA5KDM4EALDH1A1HDAC6 | |
| SCHEMBL3314915 | 0.82 | HDAC6 (0.42) | PTPN1KCNA5KDM4EALDH1A1HDAC6 | |
| SCHEMBL30338466 | 0.81 | HDAC1 (0.43) | KDM4EALDH1A1HDAC6HDAC1LMNA | |
| SCHEMBL4069997 | 0.80 | PDE4A (0.42) | PTPN1KCNA5ALDH1A1HDAC6CXCR3 | |
| SCHEMBL4250911 | 0.78 | CXCR4 (0.47) | CXCR4 | |
| SCHEMBL29824000 | 0.77 | CXCR4 (0.46) | KCNA5KDM4EALDH1A1HDAC6HDAC1 | |
| SCHEMBL1872787 | 0.77 | CXCR4 (0.46) | KCNA5KDM4EALDH1A1HDAC6HDAC1 | |
| SCHEMBL30338365 | 0.76 | HDAC6 (0.51) | KCNA5HDAC6HDAC1CXCR3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183273-B2 | Chemokine receptor binding heterocyclic compounds | ANORMED, INC. (CA) | 2007-02-27 | — | — | US | disclosed |
| US-20040235823-A1 | Chemokine receptor binding heterocyclic compounds | GENZYME CORPORATION | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235823-A1 | Chemokine receptor binding heterocyclic compounds | CCR5, CXCR4, CXCR1 | PTPN1 1129/4885KCNA5 1862/4885KDM4E 4473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.