Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 19/20 | 0.82 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.65 |
| ▸ | CCR4 | P51679 | 2/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5576521 | 1.00 | CCR5 (0.82) | CCR5KCNH2CCR4OPRM1OPRK1 | |
| SCHEMBL5576623 | 0.94 | CCR5 (0.86) | CCR5KCNH2CCR4 | |
| SCHEMBL5576629 | 0.94 | CCR5 (0.86) | CCR5KCNH2CCR4 | |
| SCHEMBL5572447 | 0.93 | CCR5 (0.89) | CCR5KCNH2CCR4OPRM1OPRK1 | |
| SCHEMBL5572446 | 0.93 | CCR5 (0.89) | CCR5KCNH2CCR4OPRM1OPRK1 | |
| SCHEMBL14614209 | 0.87 | CCR5 (0.90) | CCR5KCNH2CCR4 | |
| SCHEMBL4609766 | 0.87 | CCR5 (0.69) | CCR5KCNH2CCR4 | |
| SCHEMBL4597285 | 0.87 | CCR5 (0.69) | CCR5KCNH2CCR4 | |
| SCHEMBL4597104 | 0.86 | CCR5 (1.00) | CCR5KCNH2CCR4 | |
| SCHEMBL4597100 | 0.86 | CCR5 (1.00) | CCR5KCNH2CCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070066624-A1 | Chemokine receptor binding compounds | ANORMED, INC. (CA) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066624-A1 | Chemokine receptor binding compounds | CCR5, CCR4, CCR1 | CCR5 1/4885KCNH2 4762/4885CCR4 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.