Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.48 |
| ▸ | EDNRA | P25101 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 2/20 | 0.44 |
| ▸ | PDE4A | P27815 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MDH2 | P40926 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27599395 | 0.96 | DPP4 (0.48) | DPP4EDNRAPDE5APDE4APDE4B | |
| SCHEMBL5233228 | 0.91 | PDE5A (0.52) | DPP4EDNRAPDE5APDE4APDE4B | |
| SCHEMBL5235815 | 0.89 | NMT1 (0.49) | DPP4PDE5APDE4APDE4BPDE4C | |
| SCHEMBL5240152 | 0.88 | DPP4 (0.44) | DPP4EDNRAPDE5APDE4APDE4B | |
| SCHEMBL5231509 | 0.88 | DPP4 (0.59) | DPP4EDNRAPDE5APDE4APDE4B | |
| SCHEMBL5235849 | 0.87 | MAPK8 (0.50) | DPP4EDNRAPDE5APDE4APDE4B | |
| SCHEMBL5234388 | 0.85 | DPP4 (0.58) | DPP4EDNRA | |
| SCHEMBL5238135 | 0.85 | NMT1 (0.47) | DPP4MAOBALDH1A1 | |
| SCHEMBL5236803 | 0.84 | DPP4 (0.44) | DPP4EDNRAPDE5APDE4APDE4B | |
| SCHEMBL5239642 | 0.84 | DPP4 (0.45) | DPP4EDNRAMAOBHRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070117840-A1 | Receptor antagonist | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-05-24 | — | — | US | disclosed |
| EP-1604983-A1 | RECEPTOR ANTAGONIST | Takeda Pharmaceutical Company Limited (JP) | 2005-12-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070117840-A1 | Receptor antagonist | FSHR, NR4A1, GHRHR | DPP4 3633/4885EDNRA 90/4885PDE5A 3155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.