Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17091536 | 1.00 | GBA1 (0.47) | GBA1CYP2D6CACNA1FCHRM2CHRM1 | |
| SCHEMBL12205817 | 0.81 | HRH1 (0.52) | CYP2D6CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL468965 | 0.79 | DPP4 (0.45) | CYP2D6CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL13900797 | 0.78 | TAAR1 (0.59) | CYP2D6CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL24724279 | 0.77 | TAAR1 (0.57) | GBA1CYP2D6HRH1SLC6A3KCNH2 | |
| SCHEMBL8227223 | 0.77 | TAAR1 (0.57) | GBA1CYP2D6HRH1SLC6A3KCNH2 | |
| SCHEMBL14143114 | 0.77 | TAAR1 (0.57) | GBA1CYP2D6HRH1SLC6A3KCNH2 | |
| SCHEMBL421051 | 0.76 | KDM4E (0.61) | CYP2D6ADRA1AOPRK1SLC6A3AOC3 | |
| SCHEMBL421063 | 0.76 | KDM4E (0.61) | CYP2D6ADRA1AOPRK1SLC6A3AOC3 | |
| SCHEMBL3672484 | 0.76 | KDM4E (0.61) | CYP2D6ADRA1AOPRK1SLC6A3AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070066624-A1 | Chemokine receptor binding compounds | ANORMED, INC. (CA) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066624-A1 | Chemokine receptor binding compounds | CCR5, CCR4, CCR1 | GBA1 3249/4885CYP2D6 3925/4885CACNA1F 4248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.