SCHEMBL5576855

SCHEMBL5576855

N[C@@](O)([C@H](O)CO)[C@@H](O)C=O

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.39
PAX8 Q06710 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28658954 1.00 AKR1B1 (0.39) AKR1B1PAX8
SCHEMBL770243 0.78 AKR1B1 (0.36) AKR1B1
SCHEMBL2635116 0.78 AKR1B1 (0.36) AKR1B1
SCHEMBL27630229 0.78 AKR1B1 (0.36) AKR1B1
SCHEMBL4288128 0.78 AKR1B1 (0.36) AKR1B1
SCHEMBL2635171 0.78 AKR1B1 (0.36) AKR1B1
SCHEMBL31678577 0.78 AKR1B1 (0.36) AKR1B1
SCHEMBL1764021 0.78 AKR1B1 (0.36) AKR1B1
SCHEMBL10713443 0.78 AKR1B1 (0.36) AKR1B1
SCHEMBL27671167 0.78 AKR1B1 (0.36) AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025058295-A1 GLOMERULUS-ON-CHIP AND USE THEREOF 서울대학교병원 2025-03-20 WO claimed
US-4169197-A ANTIBIOTICS THE UPJOHN COMPANY (US) 1979-09-25 US claimed
WO-2025058295-A1 GLOMERULUS-ON-CHIP AND USE THEREOF 서울대학교병원 2025-03-20 WO disclosed
EP-1757363-A2 Surface modified polymer matrices and methods for their preparation General Electric Company (US) 2007-02-28 EP disclosed
US-20070037933-A1 Surface modified polymer matrices and methods for their preparation GENERAL ELECTRIC COMPANY 2007-02-15 US disclosed
US-20050214759-A1 Enzymatic redox labelling of nucleic acids WLASSOF WJATSCHESSLAW 2005-09-29 US disclosed
EP-1468006-A1 ENZYMATIC REDOX LABELLING OF NUCLEIC ACIDS UNISEARCH LIMITED (AU) 2004-10-20 EP disclosed
WO-2003055898-A1 ENZYMATIC REDOX LABELLING OF NUCLEIC ACIDS UNISEARCH LIMITED (AU) 2003-07-10 WO disclosed
CN-1051921-C Methods of inhibiting imperfect tissue repair LILLY CO ELI (US) 2000-05-03 CN disclosed
US-5686467-A 2-PHENYL-3-AROYLBENZOTHIOPHENES ELI LILLY AND COMPANY (US) 1997-11-11 US disclosed
US-5574047-A Methods of inhibiting imperfect tissue repair ELI LILLY AND COMPANY (US) 1996-11-12 US disclosed
CN-1109330-A Methods of inhibiting imperfect tissue repair LILLY CO ELI (US) 1995-10-04 CN disclosed
EP-0664122-A1 Inhibition of imperfect tissue repair ELI LILLY AND COMPANY (US) 1995-07-26 EP disclosed