Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1764021 | 1.00 | AKR1B1 (0.36) | AKR1B1 | |
| SCHEMBL2635116 | 1.00 | AKR1B1 (0.36) | AKR1B1 | |
| SCHEMBL27671167 | 1.00 | AKR1B1 (0.36) | AKR1B1 | |
| SCHEMBL31678577 | 1.00 | AKR1B1 (0.36) | AKR1B1 | |
| Gallic Acid SCHEMBL27751464 | 0.78 | ALDH1A1 (0.44) | — | |
| SCHEMBL28658954 | 0.78 | AKR1B1 (0.39) | AKR1B1 | |
| SCHEMBL27577900 | 0.78 | AKR1B1 (0.39) | AKR1B1 | |
| SCHEMBL5576855 | 0.78 | AKR1B1 (0.39) | AKR1B1 | |
| SCHEMBL28317227 | 0.78 | AKR1B1 (0.39) | AKR1B1 | |
| SCHEMBL27751633 | 0.78 | AKR1B1 (0.39) | AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4011352-A1 | NEW COSMETICS SOLVENTS BASED ON THREE DIFFERENT COMPONENTS | Beiersdorf AG (DE) | 2022-06-15 | — | — | EP | disclosed |
| US-20090186839-A1 | Model for studying the role of genes in chemoresistance | COLD SPRING HARBOR LABORATORY (US) | 2009-07-23 | — | — | US | disclosed |
| US-20060294604-A1 | Model for studying the role of genes in tumor resistance to chemotherapy | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2006-12-28 | — | — | US | disclosed |
| EP-1137796-A4 | MICROMONOSPORA ECHINOSPORA GENES ENCODING FOR BIOSYNTHESIS OF CALICHEAMICIN AND SELF-RESISTANCE THERETO | SLOAN KETTERING INSTITUTEFOR C (US) | 2005-05-25 | — | — | EP | disclosed |
| US-6733998-B1 | FOR PROTEINS AND ENZYMES USED IN BIOSYNTHETIC PATHWAY AND CONSTRUCTION OF ARYLTETRASACCHARIDE AND AGLYCONE | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH | 2004-05-11 | — | — | US | disclosed |
| EP-1356026-A2 | MICROMONOSPORA ECHINOSPORA GENES ENCODING FOR BIOSYNTHESIS OF CALICHEAMICIN AND SELF-RESISTANCE THERETO | Sloan-Kettering Institute For Cancer Research (US) | 2003-10-29 | — | — | EP | disclosed |
| WO-2002079465-A2 | MICROMONOSPORA ECHINOSPORA GENES ENCODING FOR BIOSYNTHESIS OF CALICHEAMICIN AND SELF-RESISTANCE THERETO | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2002-10-10 | — | — | WO | disclosed |
| EP-1137796-A2 | MICROMONOSPORA ECHINOSPORA GENES ENCODING FOR BIOSYNTHESIS OF CALICHEAMICIN AND SELF-RESISTANCE THERETO | Sloan-Kettering Institute For Cancer Research (US) | 2001-10-04 | — | — | EP | disclosed |
| WO-2000037608-A2 | MICROMONOSPORA ECHINOSPORA GENES ENCODING FOR BIOSYNTHESIS OF CALICHEAMICIN AND SELF-RESISTANCE THERETO | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2000-06-29 | — | — | WO | disclosed |