Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.47 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RGS12 | O14924 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15042279 | 0.82 | MEP1B (0.54) | AKR1B1PPARDFFAR1PLA2G4BPTGDR2 | |
| SCHEMBL29824310 | 0.81 | PTGS1 (0.67) | PTGDR2CTBP2CYP1A2PTGS1AKR1C3 | |
| SCHEMBL28629916 | 0.81 | AKR1B1 (0.52) | AKR1B1PPARDFFAR1PLA2G4BPTGDR2 | |
| SCHEMBL229067 | 0.81 | PTGS1 (0.67) | PTGDR2CTBP2CYP1A2PTGS1AKR1C3 | |
| SCHEMBL415441 | 0.81 | FFAR1 (0.68) | AKR1B1FFAR1PTGDR2AKR1C3SRD5A2 | |
| SCHEMBL25081992 | 0.81 | PLA2G4B (0.62) | AKR1B1PPARDFFAR1PLA2G4BCYP4F2 | |
| SCHEMBL14825001 | 0.81 | AKR1B1 (0.52) | AKR1B1PPARDFFAR1PLA2G4BPTGDR2 | |
| SCHEMBL30278809 | 0.81 | PLA2G4B (0.62) | AKR1B1PPARDFFAR1PLA2G4BCYP4F2 | |
| SCHEMBL761677 | 0.81 | MAPK14 (0.54) | FFAR1 | |
| SCHEMBL25081990 | 0.80 | PLA2G4B (0.68) | PPARDFFAR1PLA2G4BKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847533-A1 | SIX-MEMBERED HETEROCYCLIC COMPOUND AND THE USE THEREOF | Asahi Kasei Pharma Corporation (JP) | 2007-10-24 | — | — | EP | disclosed |