Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2083842 | 0.77 | CXCR4 (0.37) | CXCR4CYP2A6 | |
| SCHEMBL5576991 | 0.76 | RAB9A (0.31) | CYP2A6RAB9A | |
| SCHEMBL2083840 | 0.74 | CYP3A4 (0.31) | — | |
| SCHEMBL2084038 | 0.71 | SMN1; SMN2 (0.38) | LMNACXCR4 | |
| SCHEMBL2085665 | 0.69 | CXCR4 (0.31) | CXCR4 | |
| SCHEMBL2081861 | 0.69 | BRD4 (0.36) | HSD17B10 | |
| SCHEMBL2083319 | 0.67 | CHRM2 (0.33) | CXCR4 | |
| SCHEMBL2083318 | 0.66 | CYP3A4 (0.30) | — | |
| SCHEMBL6214324 | 0.64 | PLAU (0.43) | LMNAMAPTCXCR4CYP2A6NPC1 | |
| SCHEMBL8104752 | 0.64 | CNR1 (0.36) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291631-B2 | CXCR4 chemokine receptor binding compounds | GENZYME CORPORATION (US) | 2007-11-06 | — | — | US | claimed |