Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 5/20 | 0.48 |
| ▸ | CA2 | P00918 | 5/20 | 0.48 |
| ▸ | CA12 | O43570 | 4/20 | 0.48 |
| ▸ | CA9 | Q16790 | 4/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.48 |
| ▸ | CA7 | P43166 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5577021 | 1.00 | RAB9A (0.49) | RAB9AMAPTCASP3SENP8SENP7 | |
| SCHEMBL38810 | 0.89 | CA12 (0.59) | RAB9AMAPTCA1CA2CA12 | |
| SCHEMBL22301323 | 0.89 | ELANE (0.42) | RAB9AMAPTCASP3SENP8SENP7 | |
| SCHEMBL22301322 | 0.89 | ELANE (0.42) | RAB9AMAPTCASP3SENP8SENP7 | |
| SCHEMBL11887265 | 0.86 | MAPT (0.67) | RAB9AMAPTCASP3SENP8SENP7 | |
| Ethylene SCHEMBL27622376 | 0.85 | CA12 (0.55) | RAB9AMAPTCA1CA2CA12 | |
| SCHEMBL19497926 | 0.84 | CA12 (0.63) | RAB9AMAPTCA1CA2CA12 | |
| SCHEMBL109451 | 0.81 | CA1 (0.61) | CA1CA2CA12CA9CA14 | |
| SCHEMBL23986228 | 0.80 | CA1 (0.77) | RAB9AMAPTCASP3SENP8SENP7 | |
| SCHEMBL12369105 | 0.80 | CA1 (0.50) | RAB9AMAPTCASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8263192-B2 | Methods for modifying surfaces | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2012-09-11 | — | — | US | disclosed |
| US-20070134420-A1 | Methods for modifying surfaces | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2007-06-14 | — | — | US | disclosed |
| WO-2005060668-A2 | METHODS OF MODIFYING SURFACES | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OFNEW YORK (US) | 2005-07-07 | — | — | WO | disclosed |