Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.35 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5577212 | 0.89 | MEN1 (0.50) | KMT2AMEN1MDM4MDM2ATM | |
| SCHEMBL5577227 | 0.79 | MEN1 (0.46) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL5577564 | 0.79 | SMN1; SMN2 (0.40) | KMT2AMEN1F10L3MBTL1ALDH1A1 | |
| SCHEMBL5577888 | 0.76 | HTR2A (0.38) | KMT2AMEN1F10 | |
| SCHEMBL18307298 | 0.74 | KMT2A (0.44) | KMT2AMEN1ALDH1A1PTGS1PTGS2 | |
| SCHEMBL5413934 | 0.73 | KMT2A (0.43) | KMT2ACTSLCTSSL3MBTL1PTGS1 | |
| SCHEMBL5413928 | 0.73 | KMT2A (0.43) | KMT2ACTSLCTSSL3MBTL1PTGS1 | |
| SCHEMBL1109144 | 0.73 | KMT2A (0.43) | KMT2ACTSLCTSSL3MBTL1PTGS1 | |
| SCHEMBL12379297 | 0.73 | KMT2A (0.43) | KMT2ACTSLCTSSL3MBTL1PTGS1 | |
| SCHEMBL1105488 | 0.73 | KMT2A (0.43) | KMT2ACTSLCTSSL3MBTL1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070142467-A1 | 3-alkylaryl aspartate compounds and their use for selective enhancement of synaptic transmission | THE UNIVERSITY OF MONTANA (US) | 2007-06-21 | — | — | US | disclosed |
| WO-2006047251-A2 | 3-ALKYLARYL ASPARTATE COMPOUNDS AND THEIR USE FOR SELECTIVE ENHANCEMENT OF SYNAPTIC TRANSMISSION | THE UNIVERSITY OF MONTANA (US) | 2006-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142467-A1 | 3-alkylaryl aspartate compounds and their use for selective enhancement of synaptic transmission | SLC1A1, SLC1A3, SLC1A2 | TACR1 1348/4885KMT2A 1036/4885MEN1 4165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.