Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | MDM4 | O15151 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5577291 | 0.89 | TACR1 (0.41) | MEN1KMT2ATRPM8ATMMDM4 | |
| SCHEMBL5577227 | 0.87 | MEN1 (0.46) | MEN1KMT2AALDH1A1POLBRAB9A | |
| SCHEMBL5577564 | 0.86 | SMN1; SMN2 (0.40) | MEN1KMT2ATRPM8ALDH1A1 | |
| SCHEMBL10339292 | 0.80 | KMT2A (0.65) | MEN1KMT2AATMALDH1A1THRB | |
| SCHEMBL18307298 | 0.79 | KMT2A (0.44) | MEN1KMT2AANPEPALDH1A1THRB | |
| SCHEMBL1774283 | 0.78 | MMP9 (0.47) | MEN1KMT2ATRPM8ANPEPMDM4 | |
| SCHEMBL1774282 | 0.78 | MMP9 (0.47) | MEN1KMT2ATRPM8ANPEPMDM4 | |
| SCHEMBL5577888 | 0.78 | HTR2A (0.38) | MEN1KMT2ANOS3NOS1NOS2 | |
| SCHEMBL5413934 | 0.78 | KMT2A (0.43) | KMT2AKLK5 | |
| SCHEMBL1109144 | 0.78 | KMT2A (0.43) | KMT2AKLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070142467-A1 | 3-alkylaryl aspartate compounds and their use for selective enhancement of synaptic transmission | THE UNIVERSITY OF MONTANA (US) | 2007-06-21 | — | — | US | disclosed |
| WO-2006047251-A2 | 3-ALKYLARYL ASPARTATE COMPOUNDS AND THEIR USE FOR SELECTIVE ENHANCEMENT OF SYNAPTIC TRANSMISSION | THE UNIVERSITY OF MONTANA (US) | 2006-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142467-A1 | 3-alkylaryl aspartate compounds and their use for selective enhancement of synaptic transmission | SLC1A1, SLC1A3, SLC1A2 | MEN1 4165/4885KMT2A 1036/4885TRPM8 1032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.