SCHEMBL5577556

SCHEMBL5577556

CC(=O)C1C[C@@H](O)CC2CC[C@@H]3[C@H](CC[C@]4(C)[C@@H]([C@H](C)CCC(=O)O)CC[C@@H]34)[C@]21C

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPBAR1 Q8TDU6 8/20 0.73
VDR P11473 4/20 0.73
CASP7 P55210 3/20 0.73
HSD17B10 Q99714 3/20 0.73
TDP1 Q9NUW8 3/20 0.73
USP2 O75604 3/20 0.73
EPHA2 P29317 3/20 0.73
TP53 P04637 2/20 0.73
MAPK1 P28482 2/20 0.73
BLM P54132 2/20 0.73
NR1H4 Q96RI1 2/20 0.73
AKR1B10 O60218 2/20 0.73
AKR1B1 P15121 2/20 0.73
LMNA P02545 2/20 0.73
MDM4 O15151 1/20 0.73
CYP3A4 P08684 1/20 0.73
MAPT P10636 1/20 0.73
HSPD1 P10809 1/20 0.73
TSHR P16473 1/20 0.73
PTPN2 P17706 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5577551 1.00 GPBAR1 (0.73) GPBAR1VDRCASP7HSD17B10TDP1
SCHEMBL11525625 0.92 GPBAR1 (0.62) GPBAR1VDRCASP7HSD17B10TDP1
SCHEMBL11525628 0.92 GPBAR1 (0.62) GPBAR1VDRCASP7HSD17B10TDP1
SCHEMBL235607 0.89 GPBAR1 (0.77) GPBAR1VDRCASP7HSD17B10TDP1
SCHEMBL235606 0.89 GPBAR1 (0.77) GPBAR1VDRCASP7HSD17B10TDP1
SCHEMBL26670009 0.89 GPBAR1 (0.77) GPBAR1VDRCASP7HSD17B10TDP1
SCHEMBL1697152 0.88 GPBAR1 (0.76) GPBAR1VDRCASP7HSD17B10TDP1
SCHEMBL1697153 0.88 GPBAR1 (0.76) GPBAR1VDRCASP7HSD17B10TDP1
SCHEMBL11530923 0.88 GPBAR1 (0.56) GPBAR1VDRCASP7HSD17B10TDP1
SCHEMBL8568004 0.87 GPBAR1 (0.61) GPBAR1VDRCASP7HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113314402-B Photoresist composition and method for manufacturing semiconductor device 台湾积体电路制造股份有限公司 2025-03-25 CN disclosed
CN-119439628-A Photoresist composition and method for forming photoresist pattern and patterning material layer 台湾积体电路制造股份有限公司 2025-02-14 CN disclosed
CN-113311661-B Photoresist underlayer composition and method for manufacturing semiconductor device 台湾积体电路制造股份有限公司 2024-10-15 CN disclosed
CN-113805435-B Photoresist and method 台湾积体电路制造股份有限公司 2024-05-28 CN disclosed
CN-117420728-A Method for manufacturing semiconductor device and photoresist composition 台湾积体电路制造股份有限公司 2024-01-19 CN disclosed
CN-111123643-B Protective composition and method for forming photoresist pattern 台湾积体电路制造股份有限公司 2023-11-07 CN disclosed
US-20070179100-A1 Protected monomers ALNYLAM PHARMACEUTICALS, INC. 2007-08-02 US disclosed
EP-1625138-A2 PROTECTED MONOMERS Alnylam Pharmaceuticals Inc. (US) 2006-02-15 EP disclosed
WO-2004094345-A2 PROTECTED MONOMERS ALNYLAM PHARMACEUTICALS INC. (US) 2004-11-04 WO disclosed
US-4145357-A STEROID DERIVATIVES AND PROCESS FOR PREPARING THE SAME CHUGAI SYIYAKU KABUSHIKI KAISHA (JP) 1979-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070179100-A1 Protected monomers PCNA, POLN, PARP1 GPBAR1 4124/4885VDR 4209/4885CASP7 1410/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.