Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 8/20 | 0.77 |
| ▸ | CASP7 | P55210 | 3/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.77 |
| ▸ | EPHA2 | P29317 | 3/20 | 0.77 |
| ▸ | VDR | P11473 | 3/20 | 0.77 |
| ▸ | TP53 | P04637 | 2/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.77 |
| ▸ | BLM | P54132 | 2/20 | 0.77 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.77 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.77 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.77 |
| ▸ | LMNA | P02545 | 2/20 | 0.77 |
| ▸ | USP2 | O75604 | 2/20 | 0.77 |
| ▸ | MAPT | P10636 | 2/20 | 0.77 |
| ▸ | MDM4 | O15151 | 1/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.77 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.77 |
| ▸ | TSHR | P16473 | 1/20 | 0.77 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL235606 | 1.00 | GPBAR1 (0.77) | GPBAR1CASP7HSD17B10TDP1EPHA2 | |
| SCHEMBL26670009 | 1.00 | GPBAR1 (0.77) | GPBAR1CASP7HSD17B10TDP1EPHA2 | |
| SCHEMBL1697153 | 0.91 | GPBAR1 (0.76) | GPBAR1CASP7HSD17B10TDP1EPHA2 | |
| SCHEMBL1697152 | 0.91 | GPBAR1 (0.76) | GPBAR1CASP7HSD17B10TDP1EPHA2 | |
| SCHEMBL476518 | 0.89 | GPBAR1 (0.73) | GPBAR1CASP7HSD17B10TDP1EPHA2 | |
| SCHEMBL1653772 | 0.89 | GPBAR1 (0.79) | GPBAR1CASP7HSD17B10TDP1EPHA2 | |
| SCHEMBL476519 | 0.89 | GPBAR1 (0.73) | GPBAR1CASP7HSD17B10TDP1EPHA2 | |
| SCHEMBL5577556 | 0.89 | GPBAR1 (0.73) | GPBAR1CASP7HSD17B10TDP1EPHA2 | |
| SCHEMBL5577551 | 0.89 | GPBAR1 (0.73) | GPBAR1CASP7HSD17B10TDP1EPHA2 | |
| SCHEMBL26601017 | 0.89 | GPBAR1 (0.62) | GPBAR1CASP7HSD17B10TDP1EPHA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210088539-A1 | AUTOMATED SAMPLE QUALITY ASSESSMENT | METABOLON, INC. | 2021-03-25 | — | — | US | disclosed |
| US-8679457-B2 | Metabolite biomarkers to distinguish Crohn's disease from ulcerative colitis and methods using the same | METABOLON, INC. (US) | 2014-03-25 | — | — | US | disclosed |
| US-20120003158-A1 | Biomarkers for Inflammatory Bowel Disease and Methods Using the Same | METABOLON, INC. | 2012-01-05 | — | — | US | disclosed |
| EP-1080103-A4 | COMPOSITIONS AND METHODS FOR NON-PARENTERAL DELIVERY OF OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS INC (US) | 2003-07-02 | — | — | EP | disclosed |
| EP-1080103-A1 | COMPOSITIONS AND METHODS FOR NON-PARENTERAL DELIVERY OF OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 2001-03-07 | — | — | EP | disclosed |
| WO-1999060012-A1 | COMPOSITIONS AND METHODS FOR NON-PARENTERAL DELIVERY OF OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 1999-11-25 | — | — | WO | disclosed |