Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5577658 | 0.94 | CHRM3 (0.47) | KMT2AMEN1CHRM3DRD2DRD3 | |
| SCHEMBL5577724 | 0.91 | ACKR3 (0.50) | KMT2AMEN1CHRM3DRD2DRD3 | |
| SCHEMBL5577295 | 0.90 | SMN1; SMN2 (0.53) | KMT2AMEN1CHRM3CCR5LMNA | |
| SCHEMBL5577332 | 0.90 | KMT2A (0.48) | KMT2AMEN1CHRM3DRD2DRD3 | |
| SCHEMBL5577427 | 0.88 | ACKR3 (0.55) | KMT2ACHRM3DRD2ALDH1A1POLB | |
| SCHEMBL5577288 | 0.88 | CHRM3 (0.56) | KMT2AMEN1CHRM3DRD2ALDH1A1 | |
| SCHEMBL5577672 | 0.88 | KMT2A (0.51) | KMT2AMEN1CHRM3CCR5LMNA | |
| SCHEMBL5577786 | 0.88 | MEN1 (0.50) | KMT2AMEN1CHRM3DRD2ALDH1A1 | |
| SCHEMBL5577414 | 0.88 | CHRM3 (0.48) | KMT2AMEN1CHRM3DRD2LMNA | |
| SCHEMBL5577402 | 0.87 | MEN1 (0.56) | KMT2AMEN1DRD2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043079-A1 | Heterocyclic compound containing nitrogen atom and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-02-22 | — | — | US | disclosed |
| EP-1616862-A1 | NITROGENOUS HETEROCYCLIC COMPOUND AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043079-A1 | Heterocyclic compound containing nitrogen atom and use thereof | HLA-DRB1, MIF, HLA-C | KMT2A 3527/4885MEN1 748/4885CHRM3 2099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.