Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753611 | 0.87 | GPBAR1 (0.39) | SMN1; SMN2 | |
| SCHEMBL5578051 | 0.86 | DYRK1A (0.32) | — | |
| SCHEMBL14454978 | 0.83 | MEN1 (0.41) | SMN1; SMN2 | |
| SCHEMBL14454987 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL4754614 | 0.81 | TERT (0.34) | — | |
| SCHEMBL14454993 | 0.80 | CDC7 (0.34) | — | |
| SCHEMBL5577951 | 0.74 | GPBAR1 (0.39) | SMN1; SMN2 | |
| SCHEMBL14454889 | 0.71 | GSK3B (0.42) | — | |
| Hydrochloric Acid SCHEMBL5577970 | 0.70 | CYP2C19 (0.32) | — | |
| SCHEMBL5577957 | 0.69 | LIMK1 (0.44) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070173488-A1 | Pyrazolothiazole Protein Kinase Modulators | SGX PHARMACEUTICALS, INC. (US) | 2007-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070173488-A1 | Pyrazolothiazole Protein Kinase Modulators | MAP4K2, MAP4K5, MAP4K3 | SMN1; SMN2 3826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.