Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.72 |
| ▸ | LMNA | P02545 | 5/20 | 0.72 |
| ▸ | MAPT | P10636 | 4/20 | 0.72 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | ALPG | P10696 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.45 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | PDE5A | O76074 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5578324 | 0.89 | KDM4E (0.72) | KDM4EALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL5577949 | 0.85 | KDM4E (0.67) | KDM4EALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL5578267 | 0.84 | KDM4E (1.00) | KDM4EALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL5578144 | 0.82 | KDM4E (0.72) | KDM4EALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL5577942 | 0.79 | KDM4E (0.71) | KDM4EALDH1A1KMT2ALMNAMAPT | |
| Hydrochloric Acid SCHEMBL5579198 | 0.76 | KDM4E (0.85) | KDM4EALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL5578145 | 0.76 | KDM4E (0.66) | KDM4EALDH1A1KMT2ALMNAMAPT | |
| Hydrochloric Acid SCHEMBL5578137 | 0.74 | KDM4E (0.80) | KDM4EALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL5578341 | 0.74 | KDM4E (0.81) | KDM4EALDH1A1KMT2ALMNAMAPT | |
| Hydrochloric Acid SCHEMBL5578125 | 0.73 | KDM4E (0.79) | KDM4EALDH1A1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232538-A1 | Uses of polypeptides | TAKEDA PHARMACEUTICAL COMPANY, LTD (JP) | 2007-10-04 | — | — | US | disclosed |
| US-20040053826-A1 | Uses of polypeptides | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-03-18 | — | — | US | disclosed |
| EP-1308513-A1 | USE OF POLYPEPTIDE | Takeda Chemical Industries, Ltd. (JP) | 2003-05-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232538-A1 | Uses of polypeptides | NPSR1, SCTR, GRPR | KDM4E 4438/4885ALDH1A1 3946/4885KMT2A 2960/4885 |
| US-20040053826-A1 | Uses of polypeptides | NPSR1, SCTR, GRPR | KDM4E 4438/4885ALDH1A1 3946/4885KMT2A 2960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.