Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Pyridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.30 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL8610474 | 0.97 | TSHR (0.60) | TSHRNAPRTTDP1ALDH1A1PLOD2 | |
| Pyridine SCHEMBL28757618 | 0.97 | TSHR (0.60) | TSHRNAPRTTDP1ALDH1A1PLOD2 | |
| Pyridine SCHEMBL180736 | 0.97 | — | — | |
| Pyridine SCHEMBL8610477 | 0.97 | TSHR (0.60) | TSHRNAPRTTDP1ALDH1A1PLOD2 | |
| Pyridine SCHEMBL10904050 | 0.94 | TSHR (0.56) | TSHRNAPRTTDP1ALDH1A1PLOD2 | |
| Pyridine SCHEMBL11518871 | 0.94 | TSHR (0.56) | TSHRNAPRTTDP1ALDH1A1PLOD2 | |
| Pyridine SCHEMBL28829571 | 0.94 | TSHR (0.56) | TSHRNAPRTTDP1ALDH1A1PLOD2 | |
| Pyridine SCHEMBL10950366 | 0.94 | TSHR (0.56) | TSHRNAPRTTDP1ALDH1A1PLOD2 | |
| Pyridine SCHEMBL28281060 | 0.94 | TSHR (0.56) | TSHRNAPRTTDP1ALDH1A1PLOD2 | |
| Pyridine SCHEMBL10708687 | 0.94 | TSHR (0.56) | TSHRNAPRTTDP1ALDH1A1PLOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112812196-B | Industrial method for producing garlic polysaccharide by using extract liquor or garlic slicing water after garlic extraction | 晨光生物科技集团股份有限公司 | 2022-11-18 | — | — | CN | disclosed |
| CN-112812196-A | Industrial method for producing garlic polysaccharide by using garlic processing waste | 晨光生物科技集团股份有限公司 | 2021-05-18 | — | — | CN | disclosed |
| US-20070274973-A1 | METHOD OF CONTROLLING FUNGAL PATHOGENS, AND AGENTS USEFUL FOR SAME | THE AUSTRALIAN NATIONAL UNIVERSITY | 2007-11-29 | — | — | US | disclosed |
| US-4818749-A | Carboxyalkyl dipeptides and medical use thereof in treating hypertension and congestive heart failure | SCHERING CORPORATION (US) | 1989-04-04 | — | — | US | disclosed |
| US-4303654-A | ANTIINFLAMMATORY | ROUSSEL UCLAF (FR) | 1981-12-01 | — | — | US | disclosed |
| US-4232015-A | ANTIINFLAMMATORY AGENTS | ROUSSEL UCLAF (FR) | 1980-11-04 | — | — | US | disclosed |
| US-4168306-A | STEROIDS, ANTIINFLAMMATORY | ROUSSEL UCLAF (FR) | 1979-09-18 | — | — | US | disclosed |