Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.53 |
| ▸ | DPP4 | P27487 | 1/20 | 0.53 |
| ▸ | ERN1 | O75460 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | CCR6 | P51684 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.51 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987302 | 0.88 | KMT2A (0.53) | TTRDPP4KMT2AMEN1PKM | |
| SCHEMBL6987299 | 0.88 | KMT2A (0.53) | TTRDPP4KMT2AMEN1PKM | |
| SCHEMBL6639628 | 0.87 | CYP1A2 (0.53) | TTRDPP4KMT2AMEN1PKM | |
| SCHEMBL20671146 | 0.87 | KMT2A (0.52) | TTRDPP4KMT2AMEN1PKM | |
| SCHEMBL6809200 | 0.87 | CYP1A2 (0.53) | TTRDPP4KMT2AMEN1PKM | |
| SCHEMBL17980391 | 0.86 | KMT2A (0.51) | TTRDPP4KMT2AMEN1PKM | |
| SCHEMBL14508734 | 0.85 | KMT2A (0.53) | TTRDPP4KMT2AMEN1PKM | |
| SCHEMBL6980282 | 0.85 | FDPS (0.51) | KMT2AMEN1PKMHPGDNPC1 | |
| SCHEMBL6980279 | 0.85 | FDPS (0.51) | KMT2AMEN1PKMHPGDNPC1 | |
| SCHEMBL1013072 | 0.84 | STAT3 (0.53) | KMT2AMEN1PKMHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | claimed |