Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
| ▸ | ICAM1 | P05362 | 10/20 | 0.42 |
| ▸ | SELE | P16581 | 10/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TYMS | P04818 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30423251 | 0.83 | ADORA2A (0.40) | NPC1RAB9ASMN1; SMN2DHFREGFR | |
| Hydrochloric Acid SCHEMBL28038564 | 0.81 | TYMS (0.41) | DHFREGFRMEN1KMT2ATYMS | |
| SCHEMBL28214521 | 0.74 | EGFR (0.39) | NPC1RAB9AMAPTPOLBMAPK1 | |
| SCHEMBL3820499 | 0.72 | EGFR (0.47) | MAPTMAPK1EGFRMEN1KMT2A | |
| SCHEMBL1346434 | 0.72 | SMN1; SMN2 (0.53) | NPC1RAB9ASMN1; SMN2DHFRICAM1 | |
| SCHEMBL14340743 | 0.72 | LMNA (0.48) | NPC1RAB9ASMN1; SMN2DHFRICAM1 | |
| SCHEMBL6213388 | 0.71 | MAPT (0.61) | NPC1RAB9ASMN1; SMN2ICAM1SELE | |
| SCHEMBL9923541 | 0.69 | IFNAR1 (0.47) | NPC1RAB9ASMN1; SMN2DHFRICAM1 | |
| SCHEMBL30548756 | 0.69 | CYP1A2 (0.53) | NPC1RAB9ASMN1; SMN2DHFRICAM1 | |
| SCHEMBL11121836 | 0.69 | CYP1A2 (0.53) | NPC1RAB9ASMN1; SMN2DHFRICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024173715-A1 | ANTIFUNGAL COMPOSITIONS AND METHODS OF USE THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2024-08-22 | — | — | WO | claimed |
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | disclosed |