Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 3/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | TTK | P33981 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 4/20 | 0.40 |
| ▸ | BECN1 | Q14457 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5579359 | 0.83 | CYP17A1 (0.46) | CYP17A1PSMB8PTGDR2BRD4MAP4K4 | |
| SCHEMBL2028684 | 0.77 | CYP17A1 (0.47) | CYP17A1PSMB8PTGDR2MAP4K4CD274 | |
| SCHEMBL20865536 | 0.74 | CYP17A1 (0.68) | CYP17A1PSMB8BRD4MAP4K4CD274 | |
| SCHEMBL12393054 | 0.74 | BRD4 (0.57) | CYP17A1PSMB8BRD4 | |
| SCHEMBL13055402 | 0.72 | CYP17A1 (0.59) | CYP17A1PSMB8PTGDR2MAP4K4MAPK14 | |
| SCHEMBL14018513 | 0.72 | XDH (0.60) | CYP17A1PSMB8PTGDR2 | |
| SCHEMBL3360413 | 0.72 | CYP17A1 (0.63) | CYP17A1PSMB8MAP4K4CD274BCL2 | |
| SCHEMBL16329523 | 0.72 | CHEK2 (0.50) | CYP17A1PSMB8BRD4MAP4K4CD274 | |
| SCHEMBL18570243 | 0.72 | CYP17A1 (0.61) | CYP17A1PSMB8MAP4K4CD274BCL2 | |
| SCHEMBL31306250 | 0.71 | CYP17A1 (0.48) | CYP17A1PSMB8MAP4K4CD274BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249591-A1 | Biaryl Amino Acids and Their Use in Dna Binding Oligomers | SPIROGEN LIMITED (GB) | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249591-A1 | Biaryl Amino Acids and Their Use in Dna Binding Oligomers | PCNA, POLL, DNA2 | CYP17A1 2879/4885PSMB8 1377/4885PTGDR2 4608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.