SCHEMBL5579513 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	KMT2A	Q03164	2/20	0.38

▸	MEN1	O00255	1/20	0.38

▸	TSHR	P16473	1/20	0.38

▸	CTSB	P07858	5/20	0.37

▸	BACE1	P56817	5/20	0.37

▸	GLS	O94925	3/20	0.36

▸	ALDH1A1	P00352	1/20	0.35

▸	HSD17B10	Q99714	1/20	0.35

▸	DGAT1	O75907	2/20	0.35

▸	SMN1; SMN2	Q16637	1/20	0.34

▸	L3MBTL1	Q9Y468	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL5579505	1.00	KMT2A (0.38)	KMT2AMEN1TSHRCTSBBACE1
SCHEMBL5579493	0.89	CYP1A2 (0.47)	KMT2AMEN1TSHRGLSALDH1A1
SCHEMBL5579494	0.89	CYP1A2 (0.47)	KMT2AMEN1TSHRGLSALDH1A1
SCHEMBL5126861	0.87	BACE1 (0.38)	KMT2AMEN1TSHRCTSBBACE1
SCHEMBL5579577	0.86	KDM4E (0.41)	KMT2AMEN1CTSBBACE1ALDH1A1
SCHEMBL5579585	0.86	KDM4E (0.41)	KMT2AMEN1CTSBBACE1ALDH1A1
SCHEMBL3354244	0.84	BACE1 (0.50)	CTSBBACE1
SCHEMBL5123964	0.80	KMT2A (0.38)	KMT2AMEN1TSHRGLSALDH1A1
SCHEMBL5580063	0.79	GRM5 (0.41)	CTSBBACE1SMN1; SMN2
SCHEMBL5125797	0.79	BACE1 (0.44)	KMT2AMEN1CTSBBACE1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-7294642-B2	1,3-Diamino-2-hydroxypropane pro-drug derivatives	ELAN PHARMACEUTICALS, INC. (US)	2007-11-13	—	—	US	claimed