Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14676083 | 1.00 | FKBP1A (0.38) | FKBP1AATMCA12CA1CA2 | |
| SCHEMBL28340933 | 1.00 | FKBP1A (0.38) | FKBP1AATMCA12CA1CA2 | |
| SCHEMBL19084114 | 0.83 | ATM (0.46) | FKBP1AATM | |
| SCHEMBL19083696 | 0.83 | ATM (0.46) | FKBP1AATM | |
| SCHEMBL1022065 | 0.83 | DPP4 (0.30) | — | |
| SCHEMBL20290461 | 0.79 | FKBP1A (0.37) | FKBP1AATM | |
| SCHEMBL29122407 | 0.78 | CA12 (0.46) | FKBP1ACA12CA1CA2CA9 | |
| SCHEMBL5742303 | 0.78 | CA12 (0.46) | FKBP1ACA12CA1CA2CA9 | |
| SCHEMBL22091994 | 0.78 | CA12 (0.46) | FKBP1ACA12CA1CA2CA9 | |
| SCHEMBL15129623 | 0.78 | TSHR (0.42) | FKBP1AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7294642-B2 | 1,3-Diamino-2-hydroxypropane pro-drug derivatives | ELAN PHARMACEUTICALS, INC. (US) | 2007-11-13 | — | — | US | claimed |