Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 10/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5579626 | 1.00 | FLT3 (0.46) | FLT3RXFP1TP53MAPTLMNA | |
| SCHEMBL6698958 | 0.84 | BACE1 (0.51) | FLT3RXFP1MEN1KMT2ARAB9A | |
| SCHEMBL5128063 | 0.80 | MAPT (0.42) | FLT3RXFP1TP53MAPTLMNA | |
| SCHEMBL5130125 | 0.80 | FLT3 (0.47) | FLT3RXFP1TP53MAPTLMNA | |
| SCHEMBL5126861 | 0.79 | BACE1 (0.38) | RXFP1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL5124329 | 0.78 | HTT (0.44) | MAPTMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL5124337 | 0.78 | HTT (0.44) | MAPTMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL5579577 | 0.78 | KDM4E (0.41) | MEN1KMT2ARAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL5579585 | 0.78 | KDM4E (0.41) | MEN1KMT2ARAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL5128065 | 0.77 | FLT3 (0.40) | FLT3RXFP1TP53MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7294642-B2 | 1,3-Diamino-2-hydroxypropane pro-drug derivatives | ELAN PHARMACEUTICALS, INC. (US) | 2007-11-13 | — | — | US | claimed |