Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TACR2 | P21452 | 8/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5416842 | 1.00 | IDO1 (0.54) | IDO1GSK3BKMT2AMEN1L3MBTL1 | |
| SCHEMBL5075727 | 0.89 | IDO1 (0.51) | IDO1GSK3BKMT2AMEN1L3MBTL1 | |
| SCHEMBL5075734 | 0.89 | IDO1 (0.51) | IDO1GSK3BKMT2AMEN1L3MBTL1 | |
| SCHEMBL6038005 | 0.80 | GSK3B (0.72) | IDO1GSK3BKMT2AMEN1L3MBTL1 | |
| SCHEMBL6038011 | 0.80 | GSK3B (0.72) | IDO1GSK3BKMT2AMEN1L3MBTL1 | |
| SCHEMBL5579410 | 0.80 | IDO1 (0.61) | IDO1GSK3BKMT2AMEN1L3MBTL1 | |
| SCHEMBL5579406 | 0.80 | IDO1 (0.61) | IDO1GSK3BKMT2AMEN1L3MBTL1 | |
| SCHEMBL5579360 | 0.79 | IDO1 (0.53) | IDO1GSK3BKMT2AMEN1L3MBTL1 | |
| SCHEMBL5147961 | 0.79 | IDO1 (0.53) | IDO1GSK3BKMT2AMEN1L3MBTL1 | |
| SCHEMBL5147967 | 0.79 | IDO1 (0.53) | IDO1GSK3BKMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070155730-A1 | Benzodiazepine And Benzopiperazine Analog Inhibitors Of Histone Deacetylase | METHYLGENE, INC. (CA) | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155730-A1 | Benzodiazepine And Benzopiperazine Analog Inhibitors Of Histone Deacetylase | HDAC5, HDAC4, HDAC3 | IDO1 1753/4885GSK3B 1113/4885KMT2A 111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.