Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.72 |
| ▸ | IDO1 | P14902 | 2/20 | 0.71 |
| ▸ | CCKBR | P32239 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TACR2 | P21452 | 6/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6038011 | 1.00 | GSK3B (0.72) | GSK3BIDO1CCKBRKMT2AMAPT | |
| Benzodiazepinedione SCHEMBL29799531 | 0.87 | IDO1 (0.65) | GSK3BIDO1CCKBRKMT2AMAPT | |
| Benzodiazepinedione SCHEMBL10832629 | 0.87 | IDO1 (0.65) | GSK3BIDO1CCKBRKMT2AMAPT | |
| Benzodiazepinedione SCHEMBL10968598 | 0.87 | IDO1 (0.65) | GSK3BIDO1CCKBRKMT2AMAPT | |
| SCHEMBL17867048 | 0.87 | IDO1 (0.76) | GSK3BIDO1KMT2AMAPTTP53 | |
| SCHEMBL13399673 | 0.87 | IDO1 (0.76) | GSK3BIDO1KMT2AMAPTTP53 | |
| SCHEMBL2042419 | 0.87 | IDO1 (0.76) | GSK3BIDO1KMT2AMAPTTP53 | |
| SCHEMBL14595068 | 0.87 | IDO1 (0.76) | GSK3BIDO1KMT2AMAPTTP53 | |
| SCHEMBL12809540 | 0.87 | IDO1 (0.76) | GSK3BIDO1KMT2AMAPTTP53 | |
| SCHEMBL5579406 | 0.86 | IDO1 (0.61) | GSK3BIDO1CCKBRKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | METHYLGENE INC. | 2006-11-23 | — | — | US | disclosed |
| WO-2006102760-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2006-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC3, HDAC11 | GSK3B 443/4885IDO1 1132/4885CCKBR 3236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.