Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3707388 | 0.79 | — | — | |
| SCHEMBL5533233 | 0.78 | SLC6A2 (0.39) | NISCH | |
| SCHEMBL17468757 | 0.66 | MAOB (0.44) | — | |
| SCHEMBL17459292 | 0.65 | ESR1 (0.40) | PNMT | |
| SCHEMBL31116796 | 0.65 | — | — | |
| SCHEMBL20198840 | 0.64 | CCR1 (0.50) | — | |
| SCHEMBL3700062 | 0.64 | CCR1 (0.30) | — | |
| SCHEMBL20297273 | 0.62 | ALDH1A1 (0.36) | PNMT | |
| SCHEMBL18325492 | 0.62 | ALDH1A1 (0.36) | PNMT | |
| SCHEMBL17459280 | 0.62 | GUSB (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120122843-A1 | Compounds and Their Use for Treatment of Amyloid Beta-Related Diseases | ASTRAZENECA AB (SE) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122843-A1 | Compounds and Their Use for Treatment of Amyloid Beta-Related Diseases | APP, BACE1, PSEN1 | NISCH 1506/4885PNMT 468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.