SCHEMBL5580245

SCHEMBL5580245

CC(C)CCCCCC=C(C#N)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.40
LMNA P02545 1/20 0.40
ATM Q13315 1/20 0.40
EP300 Q09472 1/20 0.37
KDM1A O60341 1/20 0.36
SLC16A3 O15427 1/20 0.34
SLC16A1 P53985 1/20 0.34
KDM4C Q9H3R0 2/20 0.34
KDM4A O75164 1/20 0.34
PHF8 Q9UPP1 1/20 0.34
KDM2A Q9Y2K7 1/20 0.34
BLM P54132 1/20 0.33
CDC25A P30304 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1274438 1.00 KDM4E (0.40) KDM4ELMNAATMEP300KDM1A
SCHEMBL1275063 1.00 KDM4E (0.40) KDM4ELMNAATMEP300KDM1A
SCHEMBL2400315 0.98 KDM4E (0.41) KDM4ELMNAATMEP300KDM1A
SCHEMBL360120 0.93 KDM4E (0.42) KDM4ELMNAATMKDM1ASLC16A3
SCHEMBL451000 0.86 KDM4E (0.43) KDM4ELMNAATMKDM1ASLC16A3
SCHEMBL22216231 0.84 ACE2 (0.49) EP300
SCHEMBL142755 0.81 EP300 (0.58) LMNAATMEP300BLM
SCHEMBL3149613 0.81 EP300 (0.58) LMNAATMEP300BLM
SCHEMBL973729 0.81 EP300 (0.58) LMNAATMEP300BLM
SCHEMBL7568098 0.81 EP300 (0.58) LMNAATMEP300BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116159177-A Adhesive for treating great saphenous vein and preparation method thereof 浙江伽奈维医疗科技有限公司 2023-05-26 CN claimed
EP-1562489-B1 STABILIZED POLYESTER/CYANOACRYLATE TISSUE ADHESIVE FORMULATION POLY MED INC (US) 2016-08-24 EP claimed
EP-1562489-A4 STABILIZED POLYESTER/CYANOACRYLATE TISSUE ADHESIVE FORMULATION POLY MED INC (US) 2007-01-17 EP claimed
US-7083634-B2 Stabilized polyester/cyanoacrylate tissue adhesive formulation POLY MED INC (US) 2006-08-01 US claimed
EP-1562489-A2 STABILIZED POLYESTER/CYANOACRYLATE TISSUE ADHESIVE FORMULATION Poly-Med, Inc. (US) 2005-08-17 EP claimed
US-20050042197-A1 Stabilized polyester/cyanoacrylate tissue adhesive formulation POLY-MED, INC. 2005-02-24 US claimed
WO-2004045498-A2 STABILIZED POLYESTER/CYANOACRYLATE TISSUE ADHESIVE FORMULATION POLY-MED, INC. (US) 2004-06-03 WO claimed
US-20030069535-A1 Stabilized polyester/cyanoacrylate tissue adhesive formulation POLY-MED, INC. 2003-04-10 US claimed
CN-116159177-A Adhesive for treating great saphenous vein and preparation method thereof 浙江伽奈维医疗科技有限公司 2023-05-26 CN disclosed