SCHEMBL451000

SCHEMBL451000

CC(C)CCC=C(C#N)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.43
LMNA P02545 1/20 0.43
ATM Q13315 1/20 0.43
SLC16A3 O15427 2/20 0.37
SLC16A1 P53985 2/20 0.37
CISD1 Q9NZ45 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 1/20 0.33
HPGD P15428 1/20 0.33
GPR35 Q9HC97 1/20 0.33
KDM1A O60341 1/20 0.33
EGFR P00533 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL360120 0.89 KDM4E (0.42) KDM4ELMNAATMSLC16A3SLC16A1
SCHEMBL2400315 0.87 KDM4E (0.41) KDM4ELMNAATMSLC16A3SLC16A1
SCHEMBL5580245 0.86 KDM4E (0.40) KDM4ELMNAATMSLC16A3SLC16A1
SCHEMBL1274438 0.86 KDM4E (0.40) KDM4ELMNAATMSLC16A3SLC16A1
SCHEMBL1275063 0.86 KDM4E (0.40) KDM4ELMNAATMSLC16A3SLC16A1
SCHEMBL3245889 0.82 KDM4E (0.35) KDM4ELMNAATMSLC16A3SLC16A1
SCHEMBL7563918 0.80 GRIK1 (0.42) KDM4ELMNAATMSLC16A3SLC16A1
SCHEMBL15606 0.80 GRIK1 (0.42) KDM4ELMNAATMSLC16A3SLC16A1
SCHEMBL15607 0.80 GRIK1 (0.42) KDM4ELMNAATMSLC16A3SLC16A1
SCHEMBL5109758 0.78 GRIK1 (0.39) KDM4ESLC16A3SLC16A1CISD1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3666940-A1 METHOD OF PRODUCING POLY(ALKYL CYANOACRYLATE) BASED NANO/MICROFIBERS AND USES THEREOF Charité - Universitätsmedizin Berlin (DE) 2020-06-17 EP claimed
US-9062151-B1 Protein-cyanoacrylate nanoparticles that improve wetting property of materials The United States of America, as represented by The Secretary of Agiculture (US) 2015-06-23 US claimed
EP-1455738-B1 USE OF ELECTROPHILIC MONOMERS FOR HAIR TREATMENT OREAL (FR) 2010-07-28 EP claimed
US-20020065314-A1 COMPOSITIONS AND METHOD FOR STIMULATING HAIR GROWTH S.N. BIOTECH, INC. 2002-05-30 US claimed
US-3940362-A Cross-linked cyanoacrylate adhesive compositions JOHNSON & JOHNSON (US) 1976-02-24 US claimed
WO-2025119862-A1 COMPOSITION COMPRISING N-HEPTYLCYANOACRYLATE BOSTIK SA (FR) 2025-06-12 WO disclosed
EP-4567084-A1 COMPOSITION COMPRISING N-HEPTYLCYANOACRYLATE Bostik SA (FR) 2025-06-11 EP disclosed
US-20210244023-A1 COMPOSITIONS CONTAINING MICROENCAPSULATED ORGANIC COMPOUNDS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2021-08-12 US disclosed
EP-3666940-A1 METHOD OF PRODUCING POLY(ALKYL CYANOACRYLATE) BASED NANO/MICROFIBERS AND USES THEREOF Charité - Universitätsmedizin Berlin (DE) 2020-06-17 EP disclosed
EP-2614096-B1 ADHESIVE SYSTEM, METHOD OF ASSEMBLY OF DISTINCT COMPONENTS THEREWITH TEKNOR APEX CO (US) 2018-12-05 EP disclosed
EP-3181567-A1 PYRAZOLOPYRIMIDINE COMPOUNDS AS KINASE INHIBITORS PRINCIPIA BIOPHARMA, INC. (US) 2017-06-21 EP disclosed
EP-2366721-B1 Medical kit for use during negative pressure wound therapy AESCULAP AG (DE) 2016-08-10 EP disclosed
US-20100035997-A1 KIT FOR APPLYING A POLYMERIZABLE ADHESIVE COMPOSITION TO TISSUES BROADLEY KENNETH N 2010-02-11 US disclosed
EP-1360257-B1 CYANOACRYLATE COMPOSITIONS CURABLE TO FLEXIBLE POLYMERIC MATERIALS LOCTITE R & D LTD (IE) 2007-07-25 EP disclosed
US-6977278-B1 Cyanoacrylate compositions curable to flexible polymeric materials LOCTITE (R&D) LTD. (IE) 2005-12-20 US disclosed
US-6583250-B2 Particularly to cyanoacrylate adhesives, by mixing in a polymerization initiator capable of initiating polymerization of the monomers of the adhesive, at a temperature above the polyolefin's glass transition temperature HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-06-24 US disclosed
US-20020065314-A1 COMPOSITIONS AND METHOD FOR STIMULATING HAIR GROWTH S.N. BIOTECH, INC. 2002-05-30 US disclosed
US-20010009954-A1 POLYOLEFINE MATERIALS WITH IMPROVED ADHESIVITY COGNIS DEUTSCHLAND GMBH & CO. KG (DE) 2001-07-26 US disclosed
US-5767152-A USING A CYANOCARBOXYLIC ACID S.N. BIOTECH, INC. 1998-06-16 US disclosed
US-3940362-A Cross-linked cyanoacrylate adhesive compositions JOHNSON & JOHNSON (US) 1976-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100035997-A1 KIT FOR APPLYING A POLYMERIZABLE ADHESIVE COMPOSITION TO TISSUES KIT, TEKT1, CUTA KDM4E 2358/4885LMNA 3618/4885ATM 1385/4885
US-20020065314-A1 COMPOSITIONS AND METHOD FOR STIMULATING HAIR GROWTH AREG, NGF, HDGF KDM4E 4496/4885LMNA 3582/4885ATM 4360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.