Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.61 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.61 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.61 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | RAMP3 | O60896 | 10/20 | 0.44 |
| ▸ | CALCR | P30988 | 10/20 | 0.44 |
| ▸ | VIPR2 | P41587 | 4/20 | 0.43 |
| ▸ | VIPR1 | P32241 | 4/20 | 0.43 |
| ▸ | PTH1R | Q03431 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5580302 | 1.00 | MAPK8 (0.61) | MAPK8MAPK9MAPK10KEAP1RAMP3 | |
| SCHEMBL30974409 | 0.88 | MAPK8 (0.55) | MAPK8MAPK9MAPK10KEAP1VIPR2 | |
| SCHEMBL29965273 | 0.87 | MAPK8 (0.61) | MAPK8MAPK9MAPK10KEAP1VIPR2 | |
| SCHEMBL30242269 | 0.87 | MAPK8 (0.51) | MAPK8MAPK9MAPK10KEAP1RAMP3 | |
| SCHEMBL30171144 | 0.87 | KDM1A (0.48) | MAPK8MAPK9MAPK10KEAP1RAMP3 | |
| SCHEMBL29786765 | 0.85 | MAPK8 (0.56) | MAPK8MAPK9MAPK10KEAP1VIPR2 | |
| SCHEMBL31480031 | 0.85 | MAPK8 (0.49) | MAPK8MAPK9MAPK10KEAP1RAMP3 | |
| SCHEMBL30686009 | 0.85 | MAPK8 (0.49) | MAPK8MAPK9MAPK10KEAP1 | |
| SCHEMBL6520003 | 0.85 | MAPK8 (0.45) | MAPK8MAPK9MAPK10KEAP1RAMP3 | |
| SCHEMBL29687469 | 0.85 | MAPK8 (0.48) | MAPK8MAPK9MAPK10KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7250496-B2 | Bioinformatically detectable group of novel regulatory genes and uses thereof | ROSETTA GENOMICS LTD. (IL) | 2007-07-31 | — | — | US | disclosed |
| US-20060003322-A1 | Bioinformatically detectable group of novel regulatory genes and uses thereof | GENOPTIX, INC. | 2006-01-05 | — | — | US | disclosed |