Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.48 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | NPY4R | P50391 | 10/20 | 0.45 |
| ▸ | NPY1R | P25929 | 7/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.45 |
| ▸ | NPY2R | P49146 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8720811 | 0.96 | MAPK8 (0.44) | MAPK8MAPK9MAPK10NPY4RNPY1R | |
| SCHEMBL8720817 | 0.96 | MAPK8 (0.44) | MAPK8MAPK9MAPK10NPY4RNPY1R | |
| SCHEMBL31195953 | 0.94 | MAPK8 (0.49) | MAPK8MAPK9MAPK10NPY4RNPY1R | |
| SCHEMBL29663559 | 0.94 | MAPK8 (0.46) | MAPK8MAPK9MAPK10NPY4RNPY1R | |
| SCHEMBL31480031 | 0.93 | MAPK8 (0.49) | MAPK8MAPK9MAPK10NPY4RNPY1R | |
| SCHEMBL30974427 | 0.93 | KDM1A (0.43) | MAPK8MAPK9MAPK10NPY4RNPY1R | |
| SCHEMBL29437943 | 0.93 | MAPK8 (0.43) | MAPK8MAPK9MAPK10NPY4RNPY1R | |
| SCHEMBL30440026 | 0.92 | MAPK8 (0.46) | MAPK8MAPK9MAPK10NPY4RNPY1R | |
| SCHEMBL29496505 | 0.92 | PRCP (0.42) | MAPK8MAPK9MAPK10NPY4RNPY1R | |
| SCHEMBL31181269 | 0.91 | NPY4R (0.48) | MAPK8MAPK9MAPK10NPY4RNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541402-B1 | C3A RECEPTOR AGONISTS FOR USE AGAINST ISCHEMIC BRAIN INJURY | PEKNA MARCELA (SE) | 2022-07-20 | — | — | EP | disclosed |