Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 18/20 | 0.50 |
| ▸ | PLG | P00747 | 14/20 | 0.50 |
| ▸ | PLAT | P00750 | 7/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5581245 | 0.91 | PLAU (0.56) | PLAUPLGPLAT | |
| SCHEMBL5581127 | 0.90 | PLAU (0.53) | PLAUPLGPLAT | |
| SCHEMBL5580874 | 0.89 | PLAU (0.51) | PLAUPLGPLAT | |
| Hydrochloric Acid SCHEMBL5581203 | 0.89 | PLAU (0.49) | PLAUPLGPLAT | |
| Hydrochloric Acid SCHEMBL5581590 | 0.89 | PLAU (0.53) | PLAUPLGPLAT | |
| Hydrochloric Acid SCHEMBL5581039 | 0.88 | PLAU (0.49) | PLAUPLGPLAT | |
| SCHEMBL5580907 | 0.86 | PLAU (0.54) | PLAUPLGPLAT | |
| Hydrochloric Acid SCHEMBL5581051 | 0.86 | PLAU (0.54) | PLAUPLGPLAT | |
| SCHEMBL5581172 | 0.85 | PLAU (0.47) | PLAUPLGPLAT | |
| SCHEMBL5581915 | 0.84 | PLAU (0.48) | PLAUPLGPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148164-A1 | Neonatal Fc receptor (FcRn)-binding polypeptide variants, dimeric Fc binding proteins and methods related thereto | BIOGEN IDEC MA INC. (US) | 2007-06-28 | — | — | US | disclosed |