Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.45 |
| ▸ | ANPEP | P15144 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | IL1RN | P18510 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2729126 | 0.86 | PPARG (0.58) | KMT2APPARGPPARAMMP12TSHR | |
| SCHEMBL6628870 | 0.86 | PPARG (0.58) | KMT2APPARGPPARAMMP12TSHR | |
| SCHEMBL4780746 | 0.82 | SRR (0.61) | PPARGPPARASRR | |
| Hydrochloric Acid SCHEMBL5754335 | 0.82 | SRR (0.61) | PPARGPPARASRR | |
| SCHEMBL3653035 | 0.81 | SLC1A3 (0.49) | KMT2APPARGPPARAMMP12TSHR | |
| SCHEMBL6632835 | 0.80 | SMN1; SMN2 (0.54) | KMT2APPARGPPARAMMP12TSHR | |
| SCHEMBL6632836 | 0.80 | SMN1; SMN2 (0.54) | KMT2APPARGPPARAMMP12TSHR | |
| Hydrochloric Acid SCHEMBL27655131 | 0.80 | PPARG (0.46) | KMT2APPARGPPARAMMP12TSHR | |
| SCHEMBL7507138 | 0.79 | PPARG (0.44) | KMT2APPARGPPARATSHRERAP1 | |
| SCHEMBL7495011 | 0.78 | PPARG (0.61) | KMT2APPARGPPARATSHRSRR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799208-A2 | HETEROCYCLIC AROMATIC COMPOUNDS USEFUL AS GROWTH HORMONE SECRETAGOGUES | Brystol-Myers Squibb Company (US) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006044359-A2 | HETEROCYCLIC AROMATIC COMPOUNDS USEFUL AS GROWTH HORMONE SECRETAGOGUES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-04-27 | — | — | WO | disclosed |