Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 19/20 | 0.82 |
| ▸ | PLG | P00747 | 14/20 | 0.82 |
| ▸ | PLAT | P00750 | 8/20 | 0.82 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5580959 | 1.00 | PLAU (0.82) | PLAUPLGPLATF10 | |
| SCHEMBL5581938 | 0.92 | PLAU (0.79) | PLAUPLGPLAT | |
| SCHEMBL5581946 | 0.92 | PLAU (0.79) | PLAUPLGPLAT | |
| SCHEMBL5581350 | 0.92 | PLAU (0.77) | PLAUPLGPLAT | |
| SCHEMBL5581343 | 0.92 | PLAU (0.77) | PLAUPLGPLAT | |
| SCHEMBL5581266 | 0.91 | PLAU (0.69) | PLAUPLGPLATF10 | |
| SCHEMBL5581269 | 0.91 | PLAU (0.69) | PLAUPLGPLATF10 | |
| SCHEMBL5580994 | 0.90 | PLAU (0.73) | PLAUPLGPLAT | |
| SCHEMBL5580995 | 0.90 | PLAU (0.73) | PLAUPLGPLAT | |
| SCHEMBL5581484 | 0.90 | PLAU (1.00) | PLAUPLGPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148164-A1 | Neonatal Fc receptor (FcRn)-binding polypeptide variants, dimeric Fc binding proteins and methods related thereto | BIOGEN IDEC MA INC. (US) | 2007-06-28 | — | — | US | disclosed |