SCHEMBL5580994

SCHEMBL5580994

CC[C@@H](Oc1nc(Oc2cc(C)cc(-c3cccc(CN)c3)c2)c(F)c(N(C)Cc2ccccc2)c1F)C(=O)O

nearest known ligand 0.73

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PLAU P00749 20/20 0.73
PLG P00747 16/20 0.73
PLAT P00750 11/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5580995 1.00 PLAU (0.73) PLAUPLGPLAT
SCHEMBL5581536 0.92 PLAU (0.71) PLAUPLGPLAT
SCHEMBL5581531 0.92 PLAU (0.71) PLAUPLGPLAT
SCHEMBL5581519 0.92 PLAU (0.72) PLAUPLGPLAT
SCHEMBL5581512 0.92 PLAU (0.72) PLAUPLGPLAT
SCHEMBL5580951 0.90 PLAU (0.82) PLAUPLGPLAT
SCHEMBL5580959 0.90 PLAU (0.82) PLAUPLGPLAT
SCHEMBL5581946 0.86 PLAU (0.79) PLAUPLGPLAT
SCHEMBL5581938 0.86 PLAU (0.79) PLAUPLGPLAT
SCHEMBL5581343 0.86 PLAU (0.77) PLAUPLGPLAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070148164-A1 Neonatal Fc receptor (FcRn)-binding polypeptide variants, dimeric Fc binding proteins and methods related thereto BIOGEN IDEC MA INC. (US) 2007-06-28 US disclosed