Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | Q9HBH1 | 1/20 | 0.59 | |
| ▸ | SSTR3 | P32745 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | MEF2D | Q14814 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4894982 | 0.86 | PDF (0.62) | PDFSSTR3SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL10440716 | 0.86 | PDF (0.62) | PDFSSTR3SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL11243260 | 0.82 | PDF (0.43) | PDFSSTR3SMN1; SMN2MAPTRAB9A | |
| SCHEMBL34460413 | 0.82 | PDF (0.66) | PDFSSTR3MAPTALDH1A1PLG | |
| SCHEMBL20303609 | 0.82 | PDF (0.69) | PDFSSTR3SMN1; SMN2MAPTNPC1 | |
| SCHEMBL20303610 | 0.82 | PDF (0.69) | PDFSSTR3SMN1; SMN2MAPTNPC1 | |
| SCHEMBL11243267 | 0.81 | CA1 (0.44) | PDFSSTR3SMN1; SMN2RAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL31456028 | 0.81 | PDF (0.68) | PDFSSTR3SMN1; SMN2MAPTNPC1 | |
| SCHEMBL1674876 | 0.78 | SSTR3 (0.64) | PDFSSTR3HDAC4HDAC1 | |
| SCHEMBL8681772 | 0.78 | SSTR3 (0.57) | PDFSSTR3MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070111222-A1 | Nucleic acid aptamer-based compositions and methods | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2007-05-17 | — | — | US | disclosed |
| WO-2005051174-A2 | NUCLEIC ACID APTAMER-BASED COMPOSITIONS AND METHODS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2005-06-09 | — | — | WO | disclosed |