SCHEMBL5581848

SCHEMBL5581848

CCc1ccc(-c2nc(Oc3cc(C)cc(-c4cccc(CN)c4)c3)c(F)cc2F)c(CC(=O)O)c1

nearest known ligand 0.62

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PLAU P00749 20/20 0.62
PLG P00747 14/20 0.62
PLAT P00750 8/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5580724 0.90 PLAU (0.68) PLAUPLGPLAT
SCHEMBL5581049 0.90 PLAU (0.60) PLAUPLGPLAT
SCHEMBL5582065 0.89 PLAU (0.63) PLAUPLGPLAT
SCHEMBL5581092 0.84 CFD (0.50) PLAUPLGPLAT
SCHEMBL5580997 0.83 PLAU (0.47) PLAUPLGPLAT
SCHEMBL5581231 0.81 PLAU (0.67) PLAUPLGPLAT
SCHEMBL5580795 0.80 PLAU (0.58) PLAUPLGPLAT
SCHEMBL5580722 0.79 PLAU (0.62) PLAUPLGPLAT
SCHEMBL5581547 0.79 PLAU (0.60) PLAUPLGPLAT
SCHEMBL5581505 0.79 PLAU (0.61) PLAUPLGPLAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070148164-A1 Neonatal Fc receptor (FcRn)-binding polypeptide variants, dimeric Fc binding proteins and methods related thereto BIOGEN IDEC MA INC. (US) 2007-06-28 US disclosed