Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 12/20 | 0.42 |
| ▸ | PLG | P00747 | 8/20 | 0.42 |
| ▸ | PLAT | P00750 | 5/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5580923 | 0.87 | PLAU (0.41) | PLAUPLGPLATBRD4KARS1 | |
| SCHEMBL5580874 | 0.82 | PLAU (0.51) | PLAUPLGPLATBRD4 | |
| SCHEMBL5581446 | 0.82 | PLAU (0.47) | PLAUPLGPLATBRD4 | |
| Hydrochloric Acid SCHEMBL5581213 | 0.81 | PLAU (0.46) | PLAUPLGPLATBRD4 | |
| SCHEMBL5581492 | 0.80 | PLAU (0.46) | PLAUPLGPLATBRD4 | |
| Acetic Acid SCHEMBL5581210 | 0.79 | PLAU (0.52) | PLAUPLGPLATBRD4 | |
| SCHEMBL5581450 | 0.79 | PLAU (0.51) | PLAUPLGPLATBRD4 | |
| Hydrochloric Acid SCHEMBL5580919 | 0.79 | PLAU (0.51) | PLAUPLGPLATBRD4 | |
| SCHEMBL5581251 | 0.78 | PLAU (0.53) | PLAUPLGPLAT | |
| SCHEMBL5580907 | 0.77 | PLAU (0.54) | PLAUPLGPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148164-A1 | Neonatal Fc receptor (FcRn)-binding polypeptide variants, dimeric Fc binding proteins and methods related thereto | BIOGEN IDEC MA INC. (US) | 2007-06-28 | — | — | US | disclosed |