SCHEMBL5581960

SCHEMBL5581960

CCC[C@@H](Oc1nc(Oc2cc(C#N)cc(-c3cccc(CN)c3)c2)c(F)cc1F)C(=O)O

nearest known ligand 0.76

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PLAU P00749 20/20 0.76
PLG P00747 14/20 0.76
PLAT P00750 8/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5581966 1.00 PLAU (0.76) PLAUPLGPLAT
SCHEMBL5580801 0.94 PLAU (0.79) PLAUPLGPLAT
SCHEMBL5580809 0.94 PLAU (0.79) PLAUPLGPLAT
SCHEMBL5581274 0.90 PLAU (0.78) PLAUPLGPLAT
SCHEMBL5581281 0.90 PLAU (0.78) PLAUPLGPLAT
SCHEMBL5581185 0.90 PLAU (0.74) PLAUPLGPLAT
SCHEMBL5581188 0.90 PLAU (0.74) PLAUPLGPLAT
SCHEMBL5581808 0.89 PLAU (0.86) PLAUPLGPLAT
SCHEMBL5581968 0.88 PLAU (0.87) PLAUPLGPLAT
SCHEMBL5581979 0.88 PLAU (0.87) PLAUPLGPLAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070148164-A1 Neonatal Fc receptor (FcRn)-binding polypeptide variants, dimeric Fc binding proteins and methods related thereto BIOGEN IDEC MA INC. (US) 2007-06-28 US disclosed