Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 17/20 | 0.53 |
| ▸ | CTSL | P07711 | 15/20 | 0.53 |
| ▸ | CTSS | P25774 | 14/20 | 0.53 |
| ▸ | CTSB | P07858 | 11/20 | 0.53 |
| ▸ | CTSV | O60911 | 1/20 | 0.51 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5520635 | 0.90 | CTSL (0.62) | CTSKCTSLCTSSCTSB | |
| SCHEMBL5581282 | 0.88 | CTSL (0.58) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6048160 | 0.85 | CTSL (0.54) | CTSKCTSLCTSSCTSB | |
| SCHEMBL5519863 | 0.84 | CTSL (0.59) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5519856 | 0.84 | CTSL (0.59) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL14523327 | 0.84 | CTSL (0.52) | CTSKCTSLCTSSCTSB | |
| SCHEMBL5520008 | 0.82 | CTSL (0.57) | CTSKCTSLCTSSCTSB | |
| SCHEMBL5520013 | 0.82 | CTSL (0.57) | CTSKCTSLCTSSCTSB | |
| SCHEMBL5581326 | 0.81 | CTSL (0.54) | CTSKCTSLCTSSCTSB | |
| SCHEMBL5523705 | 0.79 | CTSL (0.56) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007519744-A | — | — | 2007-07-19 | — | — | JP | claimed |
| EP-1716158-A2 | SILINANE COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | Schering Aktiengesellschaft (DE) | 2006-11-02 | — | — | EP | claimed |
| WO-2005074904-A2 | SILINANE COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-08-18 | — | — | WO | claimed |