Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | S100A4 | P26447 | 2/20 | 0.35 |
| ▸ | VHL | P40337 | 1/20 | 0.34 |
| ▸ | ELOC | Q15369 | 1/20 | 0.34 |
| ▸ | ELOB | Q15370 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TGM2 | P21980 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5582485 | 1.00 | KDM4E (0.40) | KDM4ELMNAHTTS100A4VHL | |
| SCHEMBL5315082 | 0.81 | KDM4E (0.40) | KDM4ELMNAHTTS100A4VHL | |
| SCHEMBL5315086 | 0.81 | KDM4E (0.40) | KDM4ELMNAHTTS100A4VHL | |
| SCHEMBL68088 | 0.74 | KDM4E (0.48) | KDM4ELMNAHTTS100A4VHL | |
| SCHEMBL15114816 | 0.68 | KDM4E (0.43) | KDM4ELMNAHTTS100A4VHL | |
| SCHEMBL18885171 | 0.68 | KDM4E (0.43) | KDM4ELMNAHTTS100A4VHL | |
| SCHEMBL29953606 | 0.68 | KDM4E (0.43) | KDM4ELMNAHTTS100A4VHL | |
| SCHEMBL13379167 | 0.67 | KDM4E (0.48) | KDM4ELMNAHTTS100A4VHL | |
| SCHEMBL17522054 | 0.66 | KDM4E (0.47) | KDM4ELMNAHTTS100A4VHL | |
| SCHEMBL16471902 | 0.65 | KDM4E (0.43) | KDM4ELMNAHTTVHLELOC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | claimed |