Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | Q9HBH1 | 1/20 | 0.44 | |
| ▸ | NPY4R | P50391 | 9/20 | 0.41 |
| ▸ | NPY1R | P25929 | 5/20 | 0.41 |
| ▸ | NPY2R | P49146 | 4/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 2/20 | 0.40 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15286730 | 1.00 | PDF (0.44) | PDFNPY4RNPY1RNPY2RNPY5R | |
| Hydrochloric Acid SCHEMBL4449414 | 0.99 | PDF (0.44) | PDFNPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL38651683 | 0.96 | PDF (0.51) | PDFNPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL15923684 | 0.94 | PDF (0.42) | PDFNPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL1779020 | 0.94 | PDF (0.42) | PDFNPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL1780776 | 0.92 | PDF (0.46) | PDFNPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL16446037 | 0.91 | PDF (0.50) | PDFNPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL30073980 | 0.90 | SSTR3 (0.47) | PDFMMP2SSTR3ALDH1A1MAPT | |
| SCHEMBL5756647 | 0.90 | PDF (0.45) | PDFNPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL30931251 | 0.89 | PDF (0.44) | PDFNPY4RNPY1RNPY2RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807082-A2 | FACTOR XA COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006047415-A2 | FACTOR XA COMPOUNDS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-05-04 | — | — | WO | disclosed |