SCHEMBL5582853

SCHEMBL5582853

O=C(O)c1ccc(NC(=O)c2ccc(-c3ccccc3)cc2)cc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 5/20 0.79
DEGS1 O15121 1/20 0.77
FFAR1 O14842 1/20 0.74
KMT2A Q03164 4/20 0.71
SMN1; SMN2 Q16637 2/20 0.71
RAB9A P51151 2/20 0.71
ALDH1A1 P00352 1/20 0.71
PKM P14618 1/20 0.71
CRHBP P24387 1/20 0.71
CRHR2 Q13324 1/20 0.71
NPSR1 Q6W5P4 1/20 0.71
TDP1 Q9NUW8 1/20 0.71
TRPV1 Q8NER1 1/20 0.71
POLB P06746 3/20 0.70
STAT3 P40763 1/20 0.70
NR1H4 Q96RI1 1/20 0.69
MEN1 O00255 3/20 0.67
PSMD14 O00487 1/20 0.67
MAPT P10636 1/20 0.67
RECQL P46063 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalic Acid SCHEMBL28872662 0.96 PTPN1 (0.85) PTPN1DEGS1FFAR1KMT2ASMN1; SMN2
SCHEMBL16592197 0.94 PTPN1 (0.75) PTPN1DEGS1FFAR1KMT2ASMN1; SMN2
SCHEMBL3659600 0.90 FFAR1 (0.89) PTPN1FFAR1KMT2ASMN1; SMN2RAB9A
SCHEMBL10136221 0.90 PTPN1 (0.96) PTPN1DEGS1KMT2ASMN1; SMN2RAB9A
SCHEMBL2026664 0.90 PTPN1 (0.96) PTPN1DEGS1KMT2ASMN1; SMN2RAB9A
SCHEMBL14160276 0.90 PTPN1 (0.96) PTPN1DEGS1KMT2ASMN1; SMN2RAB9A
SCHEMBL30549187 0.88 PTPN1 (1.00) PTPN1DEGS1KMT2ASMN1; SMN2RAB9A
SCHEMBL3659389 0.88 FFAR1 (0.79) PTPN1FFAR1KMT2ARAB9AALDH1A1
SCHEMBL18085798 0.88 PTPN1 (1.00) PTPN1DEGS1FFAR1KMT2ASMN1; SMN2
SCHEMBL28419632 0.88 MITF (0.81) PTPN1FFAR1KMT2ARAB9APKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3049387-B1 THERMOPLASTIC POLYMER COMPOSITION MILLIKEN & CO (US) 2020-11-11 EP disclosed
EP-3049387-B1 THERMOPLASTIC POLYMER COMPOSITION MILLIKEN & CO (US) 2020-11-11 EP disclosed
EP-3049388-B1 NUCLEATING AGENT FOR THERMOPLASTIC POLYMER COMPOSITION MILLIKEN & CO (US) 2019-08-07 EP disclosed
EP-3049388-B1 NUCLEATING AGENT FOR THERMOPLASTIC POLYMER COMPOSITION MILLIKEN & CO (US) 2019-08-07 EP disclosed
EP-3049468-A1 THERMOPLASTIC POLYMER COMPOSITION Milliken & Company (US) 2016-08-03 EP disclosed
EP-3049388-A1 THERMOPLASTIC POLYMER COMPOSITION Milliken & Company (US) 2016-08-03 EP disclosed
EP-3049469-A1 THERMOPLASTIC POLYMER COMPOSITION Milliken & Company (US) 2016-08-03 EP disclosed
EP-3049387-A1 THERMOPLASTIC POLYMER COMPOSITION Milliken & Company (US) 2016-08-03 EP disclosed
US-9200142-B2 Thermoplastic polymer composition MILLIKEN & COMPANY (US) 2015-12-01 US disclosed
US-9200142-B2 Thermoplastic polymer composition MILLIKEN & COMPANY (US) 2015-12-01 US disclosed
US-20070173498-A1 Melanin concentrating hormone antagonist KATO KANEYOSHI 2007-07-26 US disclosed
US-20070173498-A1 Melanin concentrating hormone antagonist KATO KANEYOSHI 2007-07-26 US disclosed
US-20070173498-A1 Melanin concentrating hormone antagonist KATO KANEYOSHI 2007-07-26 US disclosed
US-7115750-B1 Melanin concentrating hormone antagonist TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2006-10-03 US disclosed
EP-1439834-A1 OXINDOLE HYDRAZIDE MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) Applied Research Systems ARS Holding N.V. (AN) 2004-07-28 EP disclosed
US-6586475-B1 5-chloro-N-(2-N,N-diethylamino)ethyl)-2- methoxy-4-(1-naphthoylamino)benzamide and prodrugs, used for prevention of neurodegenarative diseases such as Alzheimer's disease TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2003-07-01 US disclosed
WO-2003037328-A1 OXINDOLE HYDRAZIDE MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) 2003-05-08 WO disclosed
EP-1218336-A2 MELANIN CONCENTRATING HORMONE ANTAGONIST Takeda Chemical Industries, Ltd. (JP) 2002-07-03 EP disclosed
EP-1132376-A1 BETA-AMYLOID PROTEIN PRODUCTION/SECRETION INHIBITORS Takeda Chemical Industries, Ltd. (JP) 2001-09-12 EP disclosed
WO-2001021577-A2 MELANIN CONCENTRATING HORMONE ANTAGONIST TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2001-03-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070173498-A1 Melanin concentrating hormone antagonist MC1R, MCHR1, MCHR2 PTPN1 285/4885DEGS1 4436/4885FFAR1 683/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.