Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.49 |
| ▸ | CDC25C | P30307 | 2/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 4/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GRK6 | P43250 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29559399 | 0.87 | MAPT (0.56) | MAPTNPSR1PTGS2CDC25CBACE1 | |
| SCHEMBL8744275 | 0.87 | MAPT (0.56) | MAPTNPSR1PTGS2CDC25CBACE1 | |
| SCHEMBL10604334 | 0.83 | MAPT (0.60) | MAPTNPSR1PTGS2CDC25CBACE1 | |
| SCHEMBL17919915 | 0.80 | MAPT (0.55) | MAPTNPSR1PTGS2CDC25CBACE1 | |
| SCHEMBL31361989 | 0.78 | MAPT (0.72) | MAPTNPSR1PTGS2BACE1ACHE | |
| SCHEMBL31672310 | 0.77 | TSHR (0.60) | MAPTACHEALDH1A1TSHRGRK6 | |
| SCHEMBL11832913 | 0.77 | MAPT (0.66) | MAPTNPSR1PTGS2CDC25CBACE1 | |
| SCHEMBL68019 | 0.77 | TSHR (0.60) | MAPTACHEALDH1A1TSHRGRK6 | |
| SCHEMBL10600463 | 0.77 | MAPT (0.49) | MAPTNPSR1PTGS2CDC25CBACE1 | |
| SCHEMBL10600469 | 0.77 | MAPT (0.49) | MAPTNPSR1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7301049-B2 | Photolabile esters and their uses | THE INSTITUTE OF CANCER RESEARCH (GB) | 2007-11-27 | — | — | US | disclosed |
| US-20040242653-A1 | Photolabile esters and their uses | THE INSTITUTE OF CANCER RESEARCH (GB) | 2004-12-02 | — | — | US | disclosed |
| EP-1399412-A1 | PHOTOLABILE ESTERS AND THEIR USES | The Institute of Cancer Research (GB) | 2004-03-24 | — | — | EP | disclosed |
| WO-2003000644-A1 | PHOTOLABILE ESTERS AND THEIR USES | THE INSTITUTE OF CANCER RESEARCH (GB) | 2003-01-03 | — | — | WO | disclosed |
| US-5508141-A | AQUEOUS ACIDIC PHOTORESIST EMULSION CONTAINING RESIN, POSITIVE-ACTING PHOTOACTIVE FUNCTIONALITY, ACID, OXIDIZING AGENT, SURFACTANT | W. R. GRACE & CO.-CONN. (US) | 1996-04-16 | — | — | US | disclosed |
| EP-0468002-A4 | AUTODEPOSITION EMULSION FOR SELECTIVELY PROTECTING METALLIC SURFACES | GRACE W R & CO (US) | 1995-08-09 | — | — | EP | disclosed |
| US-5232815-A | Corrosion resistance | W. R. GRACE & CO.-CONN. (US) | 1993-08-03 | — | — | US | disclosed |
| EP-0518453-A1 | A method of making electrical circuit traces | W.R. Grace & Co.-Conn. (US) | 1992-12-16 | — | — | EP | disclosed |
| EP-0468002-A1 | AUTODEPOSITION EMULSION FOR SELECTIVELY PROTECTING METALLIC SURFACES | W.R. GRACE & CO.-CONN. (US) | 1992-01-29 | — | — | EP | disclosed |
| WO-1991008840-A1 | AUTODEPOSITION EMULSION FOR SELECTIVELY PROTECTING METALLIC SURFACES | W.R. GRACE & CO.-CONN. (US) | 1991-06-27 | — | — | WO | disclosed |
| US-4808682-A | BLEND WITH OLEFINICALLY UNSATURATED SILICON COMPOUND | BASF AKTIENGESELLSCHAFT (DE) | 1989-02-28 | — | — | US | disclosed |
| US-4632900-A | Process for the production of images after electrodeposition of positive photoresist on electrically conductive surface | CIBA-GEIGY CORPORATION (US) | 1986-12-30 | — | — | US | disclosed |
| US-4455311-A | Imidazoquinazoline derivatives which inhibit the aggregation of blood platelets, inhibit gastric secretion or have activity on the circulatory system | HOFFMANN-LA ROCHE INC. (US) | 1984-06-19 | — | — | US | disclosed |
| EP-0073060-A1 | Imidazoquinazoline derivatives, their preparation and medicaments containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1983-03-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242653-A1 | Photolabile esters and their uses | DIMT1, DCTD, DTYMK | MAPT 949/4885NPSR1 3149/4885PTGS2 4664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.